Foxc2 overexpression enhances benefit of endothelial progenitor cells for inhibiting neointimal formation by promoting CXCR4-dependent homing

Objective Endothelial progenitor cells (EPCs) are capable of enhancing re-endothelialization and attenuating neointimal formation. However, inefficient homing limits the therapeutic efficacy of EPCs transplantation. CXCR4 plays a critical role in regulating EPCs homing. Here, we studied the effect o...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of vascular surgery 2011-06, Vol.53 (6), p.1668-1678
Hauptverfasser:	Li, Dujuan, PhD, Yan, Dan, PhD, Liu, Weishuo, PhD, Li, Mincai, PhD, Yu, Jun, PhD, Li, Yan, PhD, Qu, Zhiling, MM, Ruan, Qiurong, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Marrow Cells Cardiovascular system Cells, Cultured Chemokine CXCL12 - metabolism Disease Models, Animal Endothelial Cells - metabolism Endothelial Cells - physiology Forkhead Transcription Factors - biosynthesis Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Mice Mice, Inbred C57BL Neointima - prevention & control Radionuclide investigations Receptors, CXCR4 - metabolism Stem Cells - metabolism Stem Cells - physiology Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Up-Regulation Vascular surgery: aorta, extremities, vena cava. Surgery of the lymphatic vessels
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!