The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation
The effects of low‐intensity extremely high‐frequency electromagnetic radiation (EHF EMR; 42.2 GHz, 0.1 mW/cm2, exposure duration 20 min) on the fatty acid (FA) composition of thymic cells and blood plasma in normal mice and in mice with peritoneal inflammation were studied. It was found that the ex...
Gespeichert in:
| Veröffentlicht in: | Bioelectromagnetics 2011-07, Vol.32 (5), p.388-395 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 395 |
|---|---|
| container_issue | 5 |
| container_start_page | 388 |
| container_title | Bioelectromagnetics |
| container_volume | 32 |
| creator | Gapeyev, Andrew B. Kulagina, Tatiana P. Aripovsky, Alexander V. Chemeris, Nikolay K. |
| description | The effects of low‐intensity extremely high‐frequency electromagnetic radiation (EHF EMR; 42.2 GHz, 0.1 mW/cm2, exposure duration 20 min) on the fatty acid (FA) composition of thymic cells and blood plasma in normal mice and in mice with peritoneal inflammation were studied. It was found that the exposure of normal mice to EHF EMR increased the content of polyunsaturated FAs (PUFAs) (eicosapentaenoic and docosapentaenoic) in thymic cells. Using a model of zymosan‐induced peritoneal inflammation, it was shown that the exposure of mice to EHF EMR significantly increased the content of PUFAs (dihomo‐γ‐linolenic, arachidonic, eicosapentaenoic, docosapentaenoic, and docosahexaenoic) and reduced the content of monounsaturated FAs (MUFAs) (palmitoleic and oleic) in thymic cells. Changes in the FA composition in the blood plasma were less pronounced and manifested themselves as an increase in the level of saturated FAs during the inflammation. The data obtained support the notion that MUFAs are replaced by PUFAs that can enter into the thymic cells from the external media. Taking into account the fact that the metabolites of PUFAs are lipid messengers actively involved in inflammatory and immune reactions, we assume that the increase in the content of n‐3 and n‐6 PUFAs in phospholipids of cellular membranes facilitates the realization of anti‐inflammatory effects of EHF EMR. Bioelectromagnetics 32:388–395, 2011. © 2011 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/bem.20645 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_868379456</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>868379456</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3625-e719c85242ef40e148bce4c59308b082d64554ad16b67efab304d023f1841d733</originalsourceid><addsrcrecordid>eNp1kD1vFDEQhi0EIkeg4A8gd4hiE3-vr4QoHEE5KAgCpbG83nHOsLtObJ9y--_jcEk6qinmeV7NvAi9peSIEsKOOxiPGFFCPkMLKhltqFa_n6MFocu20UKxA_Qq5z-EEK0Jf4kOGGW6lUov0O5iAzjFAXD02NtSZmxd6DMOE7ZTCU2Y_GDH0ZaYZgzegyv5nh3ibd0VmHKoDuxKghGGGW_C1abxCW62MLm6GKqQ4mivJijB4WT7YEuI02v0wtshw5uHeYh-fj69OPnSnH9fnZ18PG8cV0w20NKl05IJBl4QoEJ3DoSTS050RzTr69dS2J6qTrXgbceJ6AnjnmpB-5bzQ_R-n3udYr0pFzOG7GAY7ARxm41WmrdLIVUlP-xJl2LOCby5TmG0aTaUmPueTe3Z_Ou5su8eUrfdCP0T-VhsBY73wG0YYP5_kvl0un6MbPZGyAV2T4ZNf41qeSvNr28r83V9-WMt1KVZ8TuxG5hJ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>868379456</pqid></control><display><type>article</type><title>The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Gapeyev, Andrew B. ; Kulagina, Tatiana P. ; Aripovsky, Alexander V. ; Chemeris, Nikolay K.</creator><creatorcontrib>Gapeyev, Andrew B. ; Kulagina, Tatiana P. ; Aripovsky, Alexander V. ; Chemeris, Nikolay K.</creatorcontrib><description>The effects of low‐intensity extremely high‐frequency electromagnetic radiation (EHF EMR; 42.2 GHz, 0.1 mW/cm2, exposure duration 20 min) on the fatty acid (FA) composition of thymic cells and blood plasma in normal mice and in mice with peritoneal inflammation were studied. It was found that the exposure of normal mice to EHF EMR increased the content of polyunsaturated FAs (PUFAs) (eicosapentaenoic and docosapentaenoic) in thymic cells. Using a model of zymosan‐induced peritoneal inflammation, it was shown that the exposure of mice to EHF EMR significantly increased the content of PUFAs (dihomo‐γ‐linolenic, arachidonic, eicosapentaenoic, docosapentaenoic, and docosahexaenoic) and reduced the content of monounsaturated FAs (MUFAs) (palmitoleic and oleic) in thymic cells. Changes in the FA composition in the blood plasma were less pronounced and manifested themselves as an increase in the level of saturated FAs during the inflammation. The data obtained support the notion that MUFAs are replaced by PUFAs that can enter into the thymic cells from the external media. Taking into account the fact that the metabolites of PUFAs are lipid messengers actively involved in inflammatory and immune reactions, we assume that the increase in the content of n‐3 and n‐6 PUFAs in phospholipids of cellular membranes facilitates the realization of anti‐inflammatory effects of EHF EMR. Bioelectromagnetics 32:388–395, 2011. © 2011 Wiley‐Liss, Inc.</description><identifier>ISSN: 0197-8462</identifier><identifier>EISSN: 1521-186X</identifier><identifier>DOI: 10.1002/bem.20645</identifier><identifier>PMID: 21287568</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Animals ; anti-inflammatory effect ; blood plasma ; Cell Line - radiation effects ; extremely high-frequency electromagnetic radiation ; fatty acids ; Fatty Acids - metabolism ; Fatty Acids - radiation effects ; Fatty Acids, Monounsaturated - metabolism ; Fatty Acids, Monounsaturated - radiation effects ; Fatty Acids, Unsaturated - metabolism ; Fatty Acids, Unsaturated - radiation effects ; Inflammation - chemically induced ; Inflammation - metabolism ; Mice ; Radiation ; Radiation Dosage ; thymus ; Thymus Gland - radiation effects ; Zymosan ; zymosan-induced peritoneal inflammation</subject><ispartof>Bioelectromagnetics, 2011-07, Vol.32 (5), p.388-395</ispartof><rights>Copyright © 2011 Wiley‐Liss, Inc.</rights><rights>Copyright © 2011 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3625-e719c85242ef40e148bce4c59308b082d64554ad16b67efab304d023f1841d733</citedby><cites>FETCH-LOGICAL-c3625-e719c85242ef40e148bce4c59308b082d64554ad16b67efab304d023f1841d733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbem.20645$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbem.20645$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21287568$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gapeyev, Andrew B.</creatorcontrib><creatorcontrib>Kulagina, Tatiana P.</creatorcontrib><creatorcontrib>Aripovsky, Alexander V.</creatorcontrib><creatorcontrib>Chemeris, Nikolay K.</creatorcontrib><title>The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation</title><title>Bioelectromagnetics</title><addtitle>Bioelectromagnetics</addtitle><description>The effects of low‐intensity extremely high‐frequency electromagnetic radiation (EHF EMR; 42.2 GHz, 0.1 mW/cm2, exposure duration 20 min) on the fatty acid (FA) composition of thymic cells and blood plasma in normal mice and in mice with peritoneal inflammation were studied. It was found that the exposure of normal mice to EHF EMR increased the content of polyunsaturated FAs (PUFAs) (eicosapentaenoic and docosapentaenoic) in thymic cells. Using a model of zymosan‐induced peritoneal inflammation, it was shown that the exposure of mice to EHF EMR significantly increased the content of PUFAs (dihomo‐γ‐linolenic, arachidonic, eicosapentaenoic, docosapentaenoic, and docosahexaenoic) and reduced the content of monounsaturated FAs (MUFAs) (palmitoleic and oleic) in thymic cells. Changes in the FA composition in the blood plasma were less pronounced and manifested themselves as an increase in the level of saturated FAs during the inflammation. The data obtained support the notion that MUFAs are replaced by PUFAs that can enter into the thymic cells from the external media. Taking into account the fact that the metabolites of PUFAs are lipid messengers actively involved in inflammatory and immune reactions, we assume that the increase in the content of n‐3 and n‐6 PUFAs in phospholipids of cellular membranes facilitates the realization of anti‐inflammatory effects of EHF EMR. Bioelectromagnetics 32:388–395, 2011. © 2011 Wiley‐Liss, Inc.</description><subject>Animals</subject><subject>anti-inflammatory effect</subject><subject>blood plasma</subject><subject>Cell Line - radiation effects</subject><subject>extremely high-frequency electromagnetic radiation</subject><subject>fatty acids</subject><subject>Fatty Acids - metabolism</subject><subject>Fatty Acids - radiation effects</subject><subject>Fatty Acids, Monounsaturated - metabolism</subject><subject>Fatty Acids, Monounsaturated - radiation effects</subject><subject>Fatty Acids, Unsaturated - metabolism</subject><subject>Fatty Acids, Unsaturated - radiation effects</subject><subject>Inflammation - chemically induced</subject><subject>Inflammation - metabolism</subject><subject>Mice</subject><subject>Radiation</subject><subject>Radiation Dosage</subject><subject>thymus</subject><subject>Thymus Gland - radiation effects</subject><subject>Zymosan</subject><subject>zymosan-induced peritoneal inflammation</subject><issn>0197-8462</issn><issn>1521-186X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1vFDEQhi0EIkeg4A8gd4hiE3-vr4QoHEE5KAgCpbG83nHOsLtObJ9y--_jcEk6qinmeV7NvAi9peSIEsKOOxiPGFFCPkMLKhltqFa_n6MFocu20UKxA_Qq5z-EEK0Jf4kOGGW6lUov0O5iAzjFAXD02NtSZmxd6DMOE7ZTCU2Y_GDH0ZaYZgzegyv5nh3ibd0VmHKoDuxKghGGGW_C1abxCW62MLm6GKqQ4mivJijB4WT7YEuI02v0wtshw5uHeYh-fj69OPnSnH9fnZ18PG8cV0w20NKl05IJBl4QoEJ3DoSTS050RzTr69dS2J6qTrXgbceJ6AnjnmpB-5bzQ_R-n3udYr0pFzOG7GAY7ARxm41WmrdLIVUlP-xJl2LOCby5TmG0aTaUmPueTe3Z_Ou5su8eUrfdCP0T-VhsBY73wG0YYP5_kvl0un6MbPZGyAV2T4ZNf41qeSvNr28r83V9-WMt1KVZ8TuxG5hJ</recordid><startdate>201107</startdate><enddate>201107</enddate><creator>Gapeyev, Andrew B.</creator><creator>Kulagina, Tatiana P.</creator><creator>Aripovsky, Alexander V.</creator><creator>Chemeris, Nikolay K.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201107</creationdate><title>The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation</title><author>Gapeyev, Andrew B. ; Kulagina, Tatiana P. ; Aripovsky, Alexander V. ; Chemeris, Nikolay K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3625-e719c85242ef40e148bce4c59308b082d64554ad16b67efab304d023f1841d733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>anti-inflammatory effect</topic><topic>blood plasma</topic><topic>Cell Line - radiation effects</topic><topic>extremely high-frequency electromagnetic radiation</topic><topic>fatty acids</topic><topic>Fatty Acids - metabolism</topic><topic>Fatty Acids - radiation effects</topic><topic>Fatty Acids, Monounsaturated - metabolism</topic><topic>Fatty Acids, Monounsaturated - radiation effects</topic><topic>Fatty Acids, Unsaturated - metabolism</topic><topic>Fatty Acids, Unsaturated - radiation effects</topic><topic>Inflammation - chemically induced</topic><topic>Inflammation - metabolism</topic><topic>Mice</topic><topic>Radiation</topic><topic>Radiation Dosage</topic><topic>thymus</topic><topic>Thymus Gland - radiation effects</topic><topic>Zymosan</topic><topic>zymosan-induced peritoneal inflammation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gapeyev, Andrew B.</creatorcontrib><creatorcontrib>Kulagina, Tatiana P.</creatorcontrib><creatorcontrib>Aripovsky, Alexander V.</creatorcontrib><creatorcontrib>Chemeris, Nikolay K.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioelectromagnetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gapeyev, Andrew B.</au><au>Kulagina, Tatiana P.</au><au>Aripovsky, Alexander V.</au><au>Chemeris, Nikolay K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation</atitle><jtitle>Bioelectromagnetics</jtitle><addtitle>Bioelectromagnetics</addtitle><date>2011-07</date><risdate>2011</risdate><volume>32</volume><issue>5</issue><spage>388</spage><epage>395</epage><pages>388-395</pages><issn>0197-8462</issn><eissn>1521-186X</eissn><abstract>The effects of low‐intensity extremely high‐frequency electromagnetic radiation (EHF EMR; 42.2 GHz, 0.1 mW/cm2, exposure duration 20 min) on the fatty acid (FA) composition of thymic cells and blood plasma in normal mice and in mice with peritoneal inflammation were studied. It was found that the exposure of normal mice to EHF EMR increased the content of polyunsaturated FAs (PUFAs) (eicosapentaenoic and docosapentaenoic) in thymic cells. Using a model of zymosan‐induced peritoneal inflammation, it was shown that the exposure of mice to EHF EMR significantly increased the content of PUFAs (dihomo‐γ‐linolenic, arachidonic, eicosapentaenoic, docosapentaenoic, and docosahexaenoic) and reduced the content of monounsaturated FAs (MUFAs) (palmitoleic and oleic) in thymic cells. Changes in the FA composition in the blood plasma were less pronounced and manifested themselves as an increase in the level of saturated FAs during the inflammation. The data obtained support the notion that MUFAs are replaced by PUFAs that can enter into the thymic cells from the external media. Taking into account the fact that the metabolites of PUFAs are lipid messengers actively involved in inflammatory and immune reactions, we assume that the increase in the content of n‐3 and n‐6 PUFAs in phospholipids of cellular membranes facilitates the realization of anti‐inflammatory effects of EHF EMR. Bioelectromagnetics 32:388–395, 2011. © 2011 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>21287568</pmid><doi>10.1002/bem.20645</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0197-8462 |
| ispartof | Bioelectromagnetics, 2011-07, Vol.32 (5), p.388-395 |
| issn | 0197-8462 1521-186X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_868379456 |
| source | MEDLINE; Access via Wiley Online Library |
| subjects | Animals anti-inflammatory effect blood plasma Cell Line - radiation effects extremely high-frequency electromagnetic radiation fatty acids Fatty Acids - metabolism Fatty Acids - radiation effects Fatty Acids, Monounsaturated - metabolism Fatty Acids, Monounsaturated - radiation effects Fatty Acids, Unsaturated - metabolism Fatty Acids, Unsaturated - radiation effects Inflammation - chemically induced Inflammation - metabolism Mice Radiation Radiation Dosage thymus Thymus Gland - radiation effects Zymosan zymosan-induced peritoneal inflammation |
| title | The role of fatty acids in anti-inflammatory effects of low-intensity extremely high-frequency electromagnetic radiation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T17%3A38%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20role%20of%20fatty%20acids%20in%20anti-inflammatory%20effects%20of%20low-intensity%20extremely%20high-frequency%20electromagnetic%20radiation&rft.jtitle=Bioelectromagnetics&rft.au=Gapeyev,%20Andrew%20B.&rft.date=2011-07&rft.volume=32&rft.issue=5&rft.spage=388&rft.epage=395&rft.pages=388-395&rft.issn=0197-8462&rft.eissn=1521-186X&rft_id=info:doi/10.1002/bem.20645&rft_dat=%3Cproquest_cross%3E868379456%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=868379456&rft_id=info:pmid/21287568&rfr_iscdi=true |