Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis

The methanolic extracts of Physalis angulata (PA extracts) have the potential for anti-angiogenic effects through the inhibition of neo-angiogenesis in the chick chorioallantoic membrane in vivo. Physalis angulata is well-known in traditional Chinese medicine as a ingredient for various herbal formu...

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Veröffentlicht in:	Journal of ethnopharmacology 2011-06, Vol.135 (3), p.762-771
Hauptverfasser:	Hseu, You-Cheng, Wu, Chi-Rei, Chang, Hsueh-Wei, Kumar, K.J. Senthil, Lin, Ming-Kuem, Chen, Chih-Sheng, Cho, Hsin-Ju, Huang, Chun-Yin, Huang, Chih-Yang, Lee, Hong-Zin, Hsieh, Wen-Tsong, Chung, Jing-Gung, Wang, Hui-Min, Yang, Hsin-Ling
Format:	Artikel
Sprache:	eng
Schlagworte:	acetates Angiogenesis Angiogenesis Inhibitors - pharmacology Angiogenesis Inhibitors - therapeutic use Animals anti-inflammatory activity Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Antineoplastic Agents, Phytogenic - pharmacology Antineoplastic Agents, Phytogenic - therapeutic use Biological and medical sciences carcinoma Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - prevention & control Carcinoma, Squamous Cell - secondary Cell Line, Tumor Cell Movement - drug effects Cell Proliferation - drug effects Chick Embryo chicks chorioallantoic membrane endothelial cells Endothelial Cells - drug effects Endothelial Cells - metabolism gelatin General pharmacology HSC-3 cells Humans HUVECs inflammation ingredients Medical sciences Metastasis Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Mouth Neoplasms - prevention & control Neoplasm Metastasis - prevention & control Neovascularization, Pathologic - prevention & control Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Physalis Physalis angulata Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use Plasminogen Inactivators - metabolism protein synthesis Tissue Inhibitor of Metalloproteinases - metabolism traditional medicine u-plasminogen activator umbilical veins Umbilical Veins - cytology Urokinase-Type Plasminogen Activator - metabolism Vascular Endothelial Growth Factor A - metabolism vascular endothelial growth factors Western blotting Wound Healing - drug effects
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