Diagnostic accuracy of magnetic resonance imaging (MRI) in the assessment of tumor invasion depth in oral/oropharyngeal cancer
Summary The purpose of the present study was to evaluate the diagnostic value of MRI for measuring invasion depth in oral/oropharyngeal carcinoma. We retrospectively reviewed pathologic specimens and MRI findings of 114 patients who were diagnosed with squamous cell carcinoma of the oral cavity and...
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| Veröffentlicht in: | Oral oncology 2011-05, Vol.47 (5), p.381-386 |
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| creator | Park, Jun-Ook Jung, So-Lyung Joo, Yong-Hoon Jung, Chan-Kwon Cho, Kwang-Jae Kim, Min-Sik |
| description | Summary The purpose of the present study was to evaluate the diagnostic value of MRI for measuring invasion depth in oral/oropharyngeal carcinoma. We retrospectively reviewed pathologic specimens and MRI findings of 114 patients who were diagnosed with squamous cell carcinoma of the oral cavity and oropharynx. Invasion depths were evaluated in pathologic specimens and by MRI. The mean histologic and MRI invasion depths were 13.57 ± 8.476 and 15.24 ± 10.700 mm, respectively. The overall Pearson’s correlation coefficient for histologic and MRI (T1W-MRI) invasion depths was 0.825, which was statistically significant ( P < 0.001). Pearson’s correlation coefficients for histologic and MRI invasion depths in oral tongue, tongue base, and tonsil cancers were 0.949, 0.941, and 0.578, respectively. The MRI invasion depth was significantly different according to nodal status in cancers of the oral tongue ( P = 0.001∗ ) and tongue base ( P = 0.003∗ ). With MRI, the invasion depth cutoff values for determining positive nodes were 9.5 and 14.5 mm in cancers of the oral tongue and tongue base, respectively. Preoperative MRI is an accurate method for measuring tumor invasion depth in oral tongue and tongue base cancers. Furthermore, it has predictive value for nodal metastasis in the oral tongue and tongue base. |
| doi_str_mv | 10.1016/j.oraloncology.2011.03.012 |
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We retrospectively reviewed pathologic specimens and MRI findings of 114 patients who were diagnosed with squamous cell carcinoma of the oral cavity and oropharynx. Invasion depths were evaluated in pathologic specimens and by MRI. The mean histologic and MRI invasion depths were 13.57 ± 8.476 and 15.24 ± 10.700 mm, respectively. The overall Pearson’s correlation coefficient for histologic and MRI (T1W-MRI) invasion depths was 0.825, which was statistically significant ( P < 0.001). Pearson’s correlation coefficients for histologic and MRI invasion depths in oral tongue, tongue base, and tonsil cancers were 0.949, 0.941, and 0.578, respectively. The MRI invasion depth was significantly different according to nodal status in cancers of the oral tongue ( P = 0.001∗ ) and tongue base ( P = 0.003∗ ). With MRI, the invasion depth cutoff values for determining positive nodes were 9.5 and 14.5 mm in cancers of the oral tongue and tongue base, respectively. Preoperative MRI is an accurate method for measuring tumor invasion depth in oral tongue and tongue base cancers. Furthermore, it has predictive value for nodal metastasis in the oral tongue and tongue base.</description><identifier>ISSN: 1368-8375</identifier><identifier>EISSN: 1879-0593</identifier><identifier>DOI: 10.1016/j.oraloncology.2011.03.012</identifier><identifier>PMID: 21459662</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Carcinoma, Squamous Cell - diagnosis ; Carcinoma, Squamous Cell - mortality ; Carcinoma, Squamous Cell - pathology ; Female ; Hematology, Oncology and Palliative Medicine ; Humans ; Lymphatic Metastasis ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Magnetic Resonance Imaging - standards ; Male ; Medical sciences ; Middle Aged ; Mouth Neoplasms - diagnosis ; Mouth Neoplasms - mortality ; Mouth Neoplasms - pathology ; Neck Dissection - methods ; Neoplasm invasion ; Neoplasm Invasiveness ; Neoplasm Staging ; Nodal metastasis ; Oral cancer ; Oropharyngeal cancer ; Oropharyngeal Neoplasms - diagnosis ; Oropharyngeal Neoplasms - mortality ; Oropharyngeal Neoplasms - pathology ; Otolaryngology ; Otorhinolaryngology. Stomatology ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Sensitivity and Specificity ; Tumors ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Oral oncology, 2011-05, Vol.47 (5), p.381-386</ispartof><rights>Elsevier Ltd</rights><rights>2011 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c530t-ec112efd18441fd31df2ae17d28d6d83db0fbe86df6ef68f064dcef3892d1d5d3</citedby><cites>FETCH-LOGICAL-c530t-ec112efd18441fd31df2ae17d28d6d83db0fbe86df6ef68f064dcef3892d1d5d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.oraloncology.2011.03.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24232036$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21459662$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Jun-Ook</creatorcontrib><creatorcontrib>Jung, So-Lyung</creatorcontrib><creatorcontrib>Joo, Yong-Hoon</creatorcontrib><creatorcontrib>Jung, Chan-Kwon</creatorcontrib><creatorcontrib>Cho, Kwang-Jae</creatorcontrib><creatorcontrib>Kim, Min-Sik</creatorcontrib><title>Diagnostic accuracy of magnetic resonance imaging (MRI) in the assessment of tumor invasion depth in oral/oropharyngeal cancer</title><title>Oral oncology</title><addtitle>Oral Oncol</addtitle><description>Summary The purpose of the present study was to evaluate the diagnostic value of MRI for measuring invasion depth in oral/oropharyngeal carcinoma. We retrospectively reviewed pathologic specimens and MRI findings of 114 patients who were diagnosed with squamous cell carcinoma of the oral cavity and oropharynx. Invasion depths were evaluated in pathologic specimens and by MRI. The mean histologic and MRI invasion depths were 13.57 ± 8.476 and 15.24 ± 10.700 mm, respectively. The overall Pearson’s correlation coefficient for histologic and MRI (T1W-MRI) invasion depths was 0.825, which was statistically significant ( P < 0.001). Pearson’s correlation coefficients for histologic and MRI invasion depths in oral tongue, tongue base, and tonsil cancers were 0.949, 0.941, and 0.578, respectively. The MRI invasion depth was significantly different according to nodal status in cancers of the oral tongue ( P = 0.001∗ ) and tongue base ( P = 0.003∗ ). With MRI, the invasion depth cutoff values for determining positive nodes were 9.5 and 14.5 mm in cancers of the oral tongue and tongue base, respectively. Preoperative MRI is an accurate method for measuring tumor invasion depth in oral tongue and tongue base cancers. Furthermore, it has predictive value for nodal metastasis in the oral tongue and tongue base.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - diagnosis</subject><subject>Carcinoma, Squamous Cell - mortality</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Female</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Lymphatic Metastasis</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Magnetic Resonance Imaging - standards</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mouth Neoplasms - diagnosis</subject><subject>Mouth Neoplasms - mortality</subject><subject>Mouth Neoplasms - pathology</subject><subject>Neck Dissection - methods</subject><subject>Neoplasm invasion</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Staging</subject><subject>Nodal metastasis</subject><subject>Oral cancer</subject><subject>Oropharyngeal cancer</subject><subject>Oropharyngeal Neoplasms - diagnosis</subject><subject>Oropharyngeal Neoplasms - mortality</subject><subject>Oropharyngeal Neoplasms - pathology</subject><subject>Otolaryngology</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Tumors</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>1368-8375</issn><issn>1879-0593</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkkuLFDEQgBtR3If-BWkEUQ8zW5V0ZzIeBNn1sbAi-DiHTFKZydiTjEn3Ql_2t5tmxgeePCVUvnrko6rqKcIcAcXFdh6T7mIwsYvrcc4AcQ58DsjuVacoF8sZtEt-v9y5kDPJF-1JdZbzFgBabOFhdcKwaZdCsNPq7srrdYi596bWxgxJm7GOrt6VKE3BRDkGHQzVvsR8WNcvPn6-fln7UPcbqnXOlPOOQj9l9cMupvJ0q7OPoba07zcTOc17EVPcb3Qaw5p0V5upZnpUPXC6y_T4eJ5X3969_Xr5YXbz6f315ZubmWk59DMyiIycRdk06CxH65gmXFgmrbCS2xW4FUlhnSAnpAPRWEOOyyWzaFvLz6vnh7r7FH8MlHu189lQ1-lAcchKCgmsXbSykK8OpEkx50RO7VP5eRoVgpr0q636W7-a9CvgqugvyU-ObYbVjuzv1F--C_DsCOhsdOdSseDzH65hnAEXhbs6cFSk3HpKKhtPxZj1iUyvbPT_N8_rf8qYzgdfOn-nkfI2DikU7QpVZgrUl2lhpn1BBECQDf8JabjCew</recordid><startdate>20110501</startdate><enddate>20110501</enddate><creator>Park, Jun-Ook</creator><creator>Jung, So-Lyung</creator><creator>Joo, Yong-Hoon</creator><creator>Jung, Chan-Kwon</creator><creator>Cho, Kwang-Jae</creator><creator>Kim, Min-Sik</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110501</creationdate><title>Diagnostic accuracy of magnetic resonance imaging (MRI) in the assessment of tumor invasion depth in oral/oropharyngeal cancer</title><author>Park, Jun-Ook ; Jung, So-Lyung ; Joo, Yong-Hoon ; Jung, Chan-Kwon ; Cho, Kwang-Jae ; Kim, Min-Sik</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c530t-ec112efd18441fd31df2ae17d28d6d83db0fbe86df6ef68f064dcef3892d1d5d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - diagnosis</topic><topic>Carcinoma, Squamous Cell - mortality</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Female</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Lymphatic Metastasis</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Magnetic Resonance Imaging - standards</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mouth Neoplasms - diagnosis</topic><topic>Mouth Neoplasms - mortality</topic><topic>Mouth Neoplasms - pathology</topic><topic>Neck Dissection - methods</topic><topic>Neoplasm invasion</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Staging</topic><topic>Nodal metastasis</topic><topic>Oral cancer</topic><topic>Oropharyngeal cancer</topic><topic>Oropharyngeal Neoplasms - diagnosis</topic><topic>Oropharyngeal Neoplasms - mortality</topic><topic>Oropharyngeal Neoplasms - pathology</topic><topic>Otolaryngology</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Tumors</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Jun-Ook</creatorcontrib><creatorcontrib>Jung, So-Lyung</creatorcontrib><creatorcontrib>Joo, Yong-Hoon</creatorcontrib><creatorcontrib>Jung, Chan-Kwon</creatorcontrib><creatorcontrib>Cho, Kwang-Jae</creatorcontrib><creatorcontrib>Kim, Min-Sik</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Oral oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Jun-Ook</au><au>Jung, So-Lyung</au><au>Joo, Yong-Hoon</au><au>Jung, Chan-Kwon</au><au>Cho, Kwang-Jae</au><au>Kim, Min-Sik</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic accuracy of magnetic resonance imaging (MRI) in the assessment of tumor invasion depth in oral/oropharyngeal cancer</atitle><jtitle>Oral oncology</jtitle><addtitle>Oral Oncol</addtitle><date>2011-05-01</date><risdate>2011</risdate><volume>47</volume><issue>5</issue><spage>381</spage><epage>386</epage><pages>381-386</pages><issn>1368-8375</issn><eissn>1879-0593</eissn><abstract>Summary The purpose of the present study was to evaluate the diagnostic value of MRI for measuring invasion depth in oral/oropharyngeal carcinoma. We retrospectively reviewed pathologic specimens and MRI findings of 114 patients who were diagnosed with squamous cell carcinoma of the oral cavity and oropharynx. Invasion depths were evaluated in pathologic specimens and by MRI. The mean histologic and MRI invasion depths were 13.57 ± 8.476 and 15.24 ± 10.700 mm, respectively. The overall Pearson’s correlation coefficient for histologic and MRI (T1W-MRI) invasion depths was 0.825, which was statistically significant ( P < 0.001). Pearson’s correlation coefficients for histologic and MRI invasion depths in oral tongue, tongue base, and tonsil cancers were 0.949, 0.941, and 0.578, respectively. The MRI invasion depth was significantly different according to nodal status in cancers of the oral tongue ( P = 0.001∗ ) and tongue base ( P = 0.003∗ ). With MRI, the invasion depth cutoff values for determining positive nodes were 9.5 and 14.5 mm in cancers of the oral tongue and tongue base, respectively. Preoperative MRI is an accurate method for measuring tumor invasion depth in oral tongue and tongue base cancers. Furthermore, it has predictive value for nodal metastasis in the oral tongue and tongue base.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>21459662</pmid><doi>10.1016/j.oraloncology.2011.03.012</doi><tpages>6</tpages></addata></record> |
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| ispartof | Oral oncology, 2011-05, Vol.47 (5), p.381-386 |
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| subjects | Adult Aged Biological and medical sciences Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Female Hematology, Oncology and Palliative Medicine Humans Lymphatic Metastasis Magnetic resonance imaging Magnetic Resonance Imaging - methods Magnetic Resonance Imaging - standards Male Medical sciences Middle Aged Mouth Neoplasms - diagnosis Mouth Neoplasms - mortality Mouth Neoplasms - pathology Neck Dissection - methods Neoplasm invasion Neoplasm Invasiveness Neoplasm Staging Nodal metastasis Oral cancer Oropharyngeal cancer Oropharyngeal Neoplasms - diagnosis Oropharyngeal Neoplasms - mortality Oropharyngeal Neoplasms - pathology Otolaryngology Otorhinolaryngology. Stomatology Predictive Value of Tests Prognosis Retrospective Studies Sensitivity and Specificity Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | Diagnostic accuracy of magnetic resonance imaging (MRI) in the assessment of tumor invasion depth in oral/oropharyngeal cancer |
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