An unusual phospholipase A2 from puff adder Bitis arietans venom – a novel blocker of nicotinic acetylcholine receptors

The venoms of snakes from Viperidae family mainly influence the function of various blood components. However, the published data indicate that these venoms contain also neuroactive components, the most studied being neurotoxic phospholipases A2 (PLA2s). Earlier we have shown (Gorbacheva et al., 200...

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Veröffentlicht in:	Toxicon (Oxford) 2011-04, Vol.57 (5), p.787-793
Hauptverfasser:	Vulfius, Catherine A., Gorbacheva, Elena V., Starkov, Vladislav G., Osipov, Alexey V., Kasheverov, Igor E., Andreeva, Tatyana V., Astashev, Maxim E., Tsetlin, Victor I., Utkin, Yuri N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blocker Chemical Fractionation Chromatography, Gel Chromatography, Ion Exchange Freshwater Humans Lymnaea stagnalis Marine Mass Spectrometry Nicotinic acetylcholine receptor Nicotinic Antagonists - isolation & purification Nicotinic Antagonists - metabolism Phospholipase A2 Phospholipases A2 - genetics Phospholipases A2 - isolation & purification Puff adder Receptors, Nicotinic - metabolism Torpedo californica Venom Viper Venoms - enzymology Viperidae
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