Development of quantitative structure–activity relationship (QSAR) models to predict the carcinogenic potency of chemicals. II. Using oral slope factor as a measure of carcinogenic potency

The overall risk associated with exposure to a chemical is determined by combining quantitative estimates of exposure to the chemical with their known health effects. For chemicals that cause carcinogenicity, oral slope factors (OSFs) and inhalation unit risks are used to quantitatively estimate the...

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Veröffentlicht in:Regulatory toxicology and pharmacology 2011-03, Vol.59 (2), p.215-226
Hauptverfasser: Wang, Nina Ching Yi, Venkatapathy, Raghuraman, Bruce, Robert Mark, Moudgal, Chandrika
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Sprache:eng
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