Paraneoplastic Clostridium septicum Infection of a Total Knee Arthroplasty
Abstract We describe a case of a well-functioning total knee arthroplasty acutely infected with Clostridium septicum . This is the first reported infection of a prosthetic joint with this organism. A search for the source of this infection uncovered a colonic malignancy. This organism is highly asso...
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| Veröffentlicht in: | The Journal of arthroplasty 2011-06, Vol.26 (4), p.666.e9-666.e11 |
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| container_end_page | 666.e11 |
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| container_issue | 4 |
| container_start_page | 666.e9 |
| container_title | The Journal of arthroplasty |
| container_volume | 26 |
| creator | Burnell, Colin D.C., BSc, MD, FRCSC Turgeon, Thomas R., BSc, MD, MPH, FRCSC Hedden, David R., MD, FRCSC Bohm, Eric R., B Eng, MD, MSc, FRCSC |
| description | Abstract We describe a case of a well-functioning total knee arthroplasty acutely infected with Clostridium septicum . This is the first reported infection of a prosthetic joint with this organism. A search for the source of this infection uncovered a colonic malignancy. This organism is highly associated with gastrointestinal malignancy, and appropriate investigation should be carried out when it is discovered. The importance of full anaerobic bacterial identification by the microbiology laboratory is underscored by this case. |
| doi_str_mv | 10.1016/j.arth.2010.07.015 |
| format | Article |
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This is the first reported infection of a prosthetic joint with this organism. A search for the source of this infection uncovered a colonic malignancy. This organism is highly associated with gastrointestinal malignancy, and appropriate investigation should be carried out when it is discovered. The importance of full anaerobic bacterial identification by the microbiology laboratory is underscored by this case.</description><identifier>ISSN: 0883-5403</identifier><identifier>EISSN: 1532-8406</identifier><identifier>DOI: 10.1016/j.arth.2010.07.015</identifier><identifier>PMID: 20870378</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adenocarcinoma - complications ; Adenocarcinoma - diagnostic imaging ; Adenocarcinoma - therapy ; Aged, 80 and over ; Anti-Bacterial Agents - therapeutic use ; Arthroplasty, Replacement, Knee - instrumentation ; Clostridium Infections - diagnosis ; Clostridium Infections - drug therapy ; Clostridium Infections - etiology ; Clostridium septicum ; Clostridium septicum - isolation & purification ; Colonic Neoplasms - complications ; Colonic Neoplasms - diagnostic imaging ; Colonic Neoplasms - therapy ; Combined Modality Therapy ; Fatal Outcome ; Female ; Humans ; infection ; Knee Prosthesis - microbiology ; malignancy ; Orthopedics ; Osteoarthritis, Knee - surgery ; Tomography, X-Ray Computed ; total knee arthroplasty</subject><ispartof>The Journal of arthroplasty, 2011-06, Vol.26 (4), p.666.e9-666.e11</ispartof><rights>Elsevier Inc.</rights><rights>2011 Elsevier Inc.</rights><rights>Copyright © 2011 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c325t-59b42850beee6564414768f5d88edaba756d0d49980d8e1609796245e3222dc13</citedby><cites>FETCH-LOGICAL-c325t-59b42850beee6564414768f5d88edaba756d0d49980d8e1609796245e3222dc13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.arth.2010.07.015$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20870378$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burnell, Colin D.C., BSc, MD, FRCSC</creatorcontrib><creatorcontrib>Turgeon, Thomas R., BSc, MD, MPH, FRCSC</creatorcontrib><creatorcontrib>Hedden, David R., MD, FRCSC</creatorcontrib><creatorcontrib>Bohm, Eric R., B Eng, MD, MSc, FRCSC</creatorcontrib><title>Paraneoplastic Clostridium septicum Infection of a Total Knee Arthroplasty</title><title>The Journal of arthroplasty</title><addtitle>J Arthroplasty</addtitle><description>Abstract We describe a case of a well-functioning total knee arthroplasty acutely infected with Clostridium septicum . This is the first reported infection of a prosthetic joint with this organism. A search for the source of this infection uncovered a colonic malignancy. This organism is highly associated with gastrointestinal malignancy, and appropriate investigation should be carried out when it is discovered. The importance of full anaerobic bacterial identification by the microbiology laboratory is underscored by this case.</description><subject>Adenocarcinoma - complications</subject><subject>Adenocarcinoma - diagnostic imaging</subject><subject>Adenocarcinoma - therapy</subject><subject>Aged, 80 and over</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Arthroplasty, Replacement, Knee - instrumentation</subject><subject>Clostridium Infections - diagnosis</subject><subject>Clostridium Infections - drug therapy</subject><subject>Clostridium Infections - etiology</subject><subject>Clostridium septicum</subject><subject>Clostridium septicum - isolation & purification</subject><subject>Colonic Neoplasms - complications</subject><subject>Colonic Neoplasms - diagnostic imaging</subject><subject>Colonic Neoplasms - therapy</subject><subject>Combined Modality Therapy</subject><subject>Fatal Outcome</subject><subject>Female</subject><subject>Humans</subject><subject>infection</subject><subject>Knee Prosthesis - microbiology</subject><subject>malignancy</subject><subject>Orthopedics</subject><subject>Osteoarthritis, Knee - surgery</subject><subject>Tomography, X-Ray Computed</subject><subject>total knee arthroplasty</subject><issn>0883-5403</issn><issn>1532-8406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVpaDZp_0APxbeevBnJ-jKUQlja5gsSSHoWWmlMtfFaW8ku7L-PzCY59JDTDMP7vsw8Q8hnCksKVJ5tljaNf5YMygDUEqh4RxZUNKzWHOR7sgCtm1pwaI7JSc4bAEqF4B_IMQOtoFF6Qa7ubLIDxl1v8xhctepjHlPwYdpWGXdlVJrLoUM3hjhUsats9RBH21fXA2J1XhZIB_P-IznqbJ_x03M9Jb9__nhYXdQ3t78uV-c3tWuYGGvRrjnTAtaIKIXknHIldSe81ujt2iohPXjethq8RiqhVa1kXGDDGPOONqfk6yF3l-LfCfNotiE77Pv5jikbLRXXVHNVlOygdCnmnLAzuxS2Nu0NBTMjNBszIzQzQgPKFITF9OU5flpv0b9aXpgVwbeDAMuR_wImk13AwaEPqWAyPoa387__Z3d9GIKz_SPuMW_ilIaCz1CTmQFzPz9x_iEFAE6Fbp4ADNaWcg</recordid><startdate>201106</startdate><enddate>201106</enddate><creator>Burnell, Colin D.C., BSc, MD, FRCSC</creator><creator>Turgeon, Thomas R., BSc, MD, MPH, FRCSC</creator><creator>Hedden, David R., MD, FRCSC</creator><creator>Bohm, Eric R., B Eng, MD, MSc, FRCSC</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201106</creationdate><title>Paraneoplastic Clostridium septicum Infection of a Total Knee Arthroplasty</title><author>Burnell, Colin D.C., BSc, MD, FRCSC ; Turgeon, Thomas R., BSc, MD, MPH, FRCSC ; Hedden, David R., MD, FRCSC ; Bohm, Eric R., B Eng, MD, MSc, FRCSC</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c325t-59b42850beee6564414768f5d88edaba756d0d49980d8e1609796245e3222dc13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adenocarcinoma - complications</topic><topic>Adenocarcinoma - diagnostic imaging</topic><topic>Adenocarcinoma - therapy</topic><topic>Aged, 80 and over</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Arthroplasty, Replacement, Knee - instrumentation</topic><topic>Clostridium Infections - diagnosis</topic><topic>Clostridium Infections - drug therapy</topic><topic>Clostridium Infections - etiology</topic><topic>Clostridium septicum</topic><topic>Clostridium septicum - isolation & purification</topic><topic>Colonic Neoplasms - complications</topic><topic>Colonic Neoplasms - diagnostic imaging</topic><topic>Colonic Neoplasms - therapy</topic><topic>Combined Modality Therapy</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Humans</topic><topic>infection</topic><topic>Knee Prosthesis - microbiology</topic><topic>malignancy</topic><topic>Orthopedics</topic><topic>Osteoarthritis, Knee - surgery</topic><topic>Tomography, X-Ray Computed</topic><topic>total knee arthroplasty</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burnell, Colin D.C., BSc, MD, FRCSC</creatorcontrib><creatorcontrib>Turgeon, Thomas R., BSc, MD, MPH, FRCSC</creatorcontrib><creatorcontrib>Hedden, David R., MD, FRCSC</creatorcontrib><creatorcontrib>Bohm, Eric R., B Eng, MD, MSc, FRCSC</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of arthroplasty</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burnell, Colin D.C., BSc, MD, FRCSC</au><au>Turgeon, Thomas R., BSc, MD, MPH, FRCSC</au><au>Hedden, David R., MD, FRCSC</au><au>Bohm, Eric R., B Eng, MD, MSc, FRCSC</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Paraneoplastic Clostridium septicum Infection of a Total Knee Arthroplasty</atitle><jtitle>The Journal of arthroplasty</jtitle><addtitle>J Arthroplasty</addtitle><date>2011-06</date><risdate>2011</risdate><volume>26</volume><issue>4</issue><spage>666.e9</spage><epage>666.e11</epage><pages>666.e9-666.e11</pages><issn>0883-5403</issn><eissn>1532-8406</eissn><abstract>Abstract We describe a case of a well-functioning total knee arthroplasty acutely infected with Clostridium septicum . This is the first reported infection of a prosthetic joint with this organism. A search for the source of this infection uncovered a colonic malignancy. This organism is highly associated with gastrointestinal malignancy, and appropriate investigation should be carried out when it is discovered. The importance of full anaerobic bacterial identification by the microbiology laboratory is underscored by this case.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>20870378</pmid><doi>10.1016/j.arth.2010.07.015</doi></addata></record> |
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| identifier | ISSN: 0883-5403 |
| ispartof | The Journal of arthroplasty, 2011-06, Vol.26 (4), p.666.e9-666.e11 |
| issn | 0883-5403 1532-8406 |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Adenocarcinoma - complications Adenocarcinoma - diagnostic imaging Adenocarcinoma - therapy Aged, 80 and over Anti-Bacterial Agents - therapeutic use Arthroplasty, Replacement, Knee - instrumentation Clostridium Infections - diagnosis Clostridium Infections - drug therapy Clostridium Infections - etiology Clostridium septicum Clostridium septicum - isolation & purification Colonic Neoplasms - complications Colonic Neoplasms - diagnostic imaging Colonic Neoplasms - therapy Combined Modality Therapy Fatal Outcome Female Humans infection Knee Prosthesis - microbiology malignancy Orthopedics Osteoarthritis, Knee - surgery Tomography, X-Ray Computed total knee arthroplasty |
| title | Paraneoplastic Clostridium septicum Infection of a Total Knee Arthroplasty |
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