Ruthenium-Catalyzed Regio- and Enantioselective Allylic Substitution with Water: Direct Synthesis of Chiral Allylic Alcohols

Less is more: A new route to access chiral allylic alcohols through the regio‐ and enantioselective substitution of monosubstituted allylic chlorides with water has been developed. The reaction is catalyzed effectively by planar‐chiral cyclopentadienyl ruthenium complexes (see scheme).

Bibliographische Detailangaben

Veröffentlicht in:	Angewandte Chemie International Edition 2011-05, Vol.50 (22), p.5197-5199
Hauptverfasser:	Kanbayashi, Naoya, Onitsuka, Kiyotaka
Format:	Artikel
Sprache:	eng
Schlagworte:	allylation asymmetric synthesis hydroxylation Ruthenium water
Online-Zugang:	Volltext
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