SIRT1 Acts as a Modulator of Neointima Formation Following Vascular Injury in Mice

RATIONALE:Vascular smooth muscle cell (VSMC) proliferation and migration are crucial events involved in the pathophysiology of vascular diseases. Sirtuin 1 (SIRT1), a class III histone deacetylase (HDAC), has been reported to have the function of antiatherosclerosis, but its role in neointima format...

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Veröffentlicht in:	Circulation research 2011-05, Vol.108 (10), p.1180-1189
Hauptverfasser:	Li, Li, Zhang, Hui-Na, Chen, Hou-Zao, Gao, Peng, Zhu, Li-Hua, Li, Hong-Liang, Lv, Xiang, Zhang, Qing-Jun, Zhang, Ran, Wang, Zhao, She, Zhi-Gang, Wei, Yu-Sheng, Du, Guan-Hua, Liu, De-Pei, Liang, Chih-Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Carotid Artery Injuries - genetics Carotid Artery Injuries - metabolism Carotid Artery Injuries - pathology Cells, Cultured Fundamental and applied biological sciences. Psychology Humans Ligation Male Mice Mice, Transgenic Neointima - etiology Neointima - metabolism Neointima - pathology Rats Rats, Sprague-Dawley Sirtuin 1 - biosynthesis Sirtuin 1 - physiology Vertebrates: cardiovascular system
Online-Zugang:	Volltext
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