Regulation of autophagy in the heart: "you only live twice"

Autophagy is a highly orchestrated cellular process by which proteins and organelles are degraded via an elaborate lysosomal pathway to generate free amino acids and sugars for ATP during metabolic stress. At present, the exact role of autophagy in the heart is highly debated but suggested to play a...

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Veröffentlicht in:	Antioxidants & redox signaling 2011-06, Vol.14 (11), p.2245-2250
Hauptverfasser:	Aviv, Yaron, Shaw, James, Gang, Hongying, Kirshenbaum, Lorrie A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Autophagy Autophagy (Cytology) Autophagy-Related Protein 5 Heart Heart failure Humans Microtubule-Associated Proteins - metabolism Myocardial Reperfusion Injury - metabolism Myocardial Reperfusion Injury - pathology Myocardium - metabolism Myocardium - pathology Phagosomes - metabolism Physiological aspects Prevention Proto-Oncogene Proteins c-bcl-2 - metabolism Stress, Physiological
Online-Zugang:	Volltext
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