A Survey on the Prevalence of Pseudotumors with Metal-on-Metal Hip Resurfacing in Canadian Academic Centers

Metal-on-metal bearings for hip arthroplasty have been in clinical use for over twenty years with excellent clinical results reported worldwide. A small percentage (

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Veröffentlicht in:Journal of bone and joint surgery. American volume 2011-05, Vol.93 (Supplement_2), p.118-121
1. Verfasser: Beaulé, Paul E.
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container_end_page 121
container_issue Supplement_2
container_start_page 118
container_title Journal of bone and joint surgery. American volume
container_volume 93
creator Beaulé, Paul E.
description Metal-on-metal bearings for hip arthroplasty have been in clinical use for over twenty years with excellent clinical results reported worldwide. A small percentage (
doi_str_mv 10.2106/JBJS.J.01848
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A small percentage (&lt;1%) of patients have developed an inflammatory response, and a more severe inflammatory response termed pseudotumor has been more recently reported. The primary purpose of this study was to determine the prevalence of pseudotumor following metal-on-metal hip resurfacing in Canadian academic centers. Nine of the fourteen centers that perform metal-on-metal hip resurfacings were surveyed. The number of metal-on-metal hip resurfacing arthroplasties performed at each center was determined, as was the number of patients who presented with a pseudotumor and subsequently required revision hip surgery between 2002 and December 2008. At the nine centers, 3432 hip resurfacing arthroplasties were performed; 76.9% of the patients were male, the mean age was 51.2 years (range, sixteen to eighty-three years), and the mean body-mass index was 28.1 (range, 17 to 55). The mean length of follow-up was 3.4 years (range, two to nine years). A pseudotumor developed after four of the 3432 arthroplasties, for a prevalence of 0.10%. Although pseudotumors remain a concern after metal-on-metal hip resurfacing, the prevalence at short to midterm follow-up is very low in this multicenter survey. Continued close monitoring is required to determine what clinical factors are involved with the uncommon pseudotumor formation.</description><identifier>ISSN: 0021-9355</identifier><identifier>EISSN: 1535-1386</identifier><identifier>DOI: 10.2106/JBJS.J.01848</identifier><identifier>PMID: 21543700</identifier><identifier>CODEN: JBJSA3</identifier><language>eng</language><publisher>Boston, MA: The Journal of Bone and Joint Surgery, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arthroplasty, Replacement, Hip - adverse effects ; Biological and medical sciences ; Canada - epidemiology ; Diseases of the osteoarticular system ; Female ; Follow-Up Studies ; Foreign-Body Reaction - epidemiology ; Foreign-Body Reaction - surgery ; Granuloma, Plasma Cell - epidemiology ; Granuloma, Plasma Cell - surgery ; Hip Prosthesis - adverse effects ; Humans ; Male ; Medical sciences ; Metals ; Middle Aged ; Orthopedic surgery ; Prevalence ; Reoperation ; Surface Properties ; Surgery (general aspects). 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American volume</title><addtitle>J Bone Joint Surg Am</addtitle><description>Metal-on-metal bearings for hip arthroplasty have been in clinical use for over twenty years with excellent clinical results reported worldwide. A small percentage (&lt;1%) of patients have developed an inflammatory response, and a more severe inflammatory response termed pseudotumor has been more recently reported. The primary purpose of this study was to determine the prevalence of pseudotumor following metal-on-metal hip resurfacing in Canadian academic centers. Nine of the fourteen centers that perform metal-on-metal hip resurfacings were surveyed. The number of metal-on-metal hip resurfacing arthroplasties performed at each center was determined, as was the number of patients who presented with a pseudotumor and subsequently required revision hip surgery between 2002 and December 2008. At the nine centers, 3432 hip resurfacing arthroplasties were performed; 76.9% of the patients were male, the mean age was 51.2 years (range, sixteen to eighty-three years), and the mean body-mass index was 28.1 (range, 17 to 55). The mean length of follow-up was 3.4 years (range, two to nine years). A pseudotumor developed after four of the 3432 arthroplasties, for a prevalence of 0.10%. Although pseudotumors remain a concern after metal-on-metal hip resurfacing, the prevalence at short to midterm follow-up is very low in this multicenter survey. Continued close monitoring is required to determine what clinical factors are involved with the uncommon pseudotumor formation.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arthroplasty, Replacement, Hip - adverse effects</subject><subject>Biological and medical sciences</subject><subject>Canada - epidemiology</subject><subject>Diseases of the osteoarticular system</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Foreign-Body Reaction - epidemiology</subject><subject>Foreign-Body Reaction - surgery</subject><subject>Granuloma, Plasma Cell - epidemiology</subject><subject>Granuloma, Plasma Cell - surgery</subject><subject>Hip Prosthesis - adverse effects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metals</subject><subject>Middle Aged</subject><subject>Orthopedic surgery</subject><subject>Prevalence</subject><subject>Reoperation</subject><subject>Surface Properties</subject><subject>Surgery (general aspects). 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Transplantations, organ and tissue grafts. Graft diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Beaulé, Paul E.</creatorcontrib><creatorcontrib>Canadian Hip Resurfacing Study Group</creatorcontrib><creatorcontrib>the Canadian Hip Resurfacing Study Group</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of bone and joint surgery. American volume</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Beaulé, Paul E.</au><aucorp>Canadian Hip Resurfacing Study Group</aucorp><aucorp>the Canadian Hip Resurfacing Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Survey on the Prevalence of Pseudotumors with Metal-on-Metal Hip Resurfacing in Canadian Academic Centers</atitle><jtitle>Journal of bone and joint surgery. American volume</jtitle><addtitle>J Bone Joint Surg Am</addtitle><date>2011-05-04</date><risdate>2011</risdate><volume>93</volume><issue>Supplement_2</issue><spage>118</spage><epage>121</epage><pages>118-121</pages><issn>0021-9355</issn><eissn>1535-1386</eissn><coden>JBJSA3</coden><abstract>Metal-on-metal bearings for hip arthroplasty have been in clinical use for over twenty years with excellent clinical results reported worldwide. A small percentage (&lt;1%) of patients have developed an inflammatory response, and a more severe inflammatory response termed pseudotumor has been more recently reported. The primary purpose of this study was to determine the prevalence of pseudotumor following metal-on-metal hip resurfacing in Canadian academic centers. Nine of the fourteen centers that perform metal-on-metal hip resurfacings were surveyed. The number of metal-on-metal hip resurfacing arthroplasties performed at each center was determined, as was the number of patients who presented with a pseudotumor and subsequently required revision hip surgery between 2002 and December 2008. At the nine centers, 3432 hip resurfacing arthroplasties were performed; 76.9% of the patients were male, the mean age was 51.2 years (range, sixteen to eighty-three years), and the mean body-mass index was 28.1 (range, 17 to 55). The mean length of follow-up was 3.4 years (range, two to nine years). A pseudotumor developed after four of the 3432 arthroplasties, for a prevalence of 0.10%. Although pseudotumors remain a concern after metal-on-metal hip resurfacing, the prevalence at short to midterm follow-up is very low in this multicenter survey. Continued close monitoring is required to determine what clinical factors are involved with the uncommon pseudotumor formation.</abstract><cop>Boston, MA</cop><pub>The Journal of Bone and Joint Surgery, Inc</pub><pmid>21543700</pmid><doi>10.2106/JBJS.J.01848</doi><tpages>4</tpages></addata></record>
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source MEDLINE; Alma/SFX Local Collection; Journals@Ovid Complete
subjects Adolescent
Adult
Aged
Aged, 80 and over
Arthroplasty, Replacement, Hip - adverse effects
Biological and medical sciences
Canada - epidemiology
Diseases of the osteoarticular system
Female
Follow-Up Studies
Foreign-Body Reaction - epidemiology
Foreign-Body Reaction - surgery
Granuloma, Plasma Cell - epidemiology
Granuloma, Plasma Cell - surgery
Hip Prosthesis - adverse effects
Humans
Male
Medical sciences
Metals
Middle Aged
Orthopedic surgery
Prevalence
Reoperation
Surface Properties
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
title A Survey on the Prevalence of Pseudotumors with Metal-on-Metal Hip Resurfacing in Canadian Academic Centers
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