Aerobic capacity and skeletal muscle function in children with asthma
Background Peripheral muscle strength and endurance are decreased in patients with chronic pulmonary diseases and seem to contribute to patients' exercise intolerance. However, the authors are not aware of any studies evaluating peripheral muscle function in children with asthma. It seems to be...
Gespeichert in:
| Veröffentlicht in: | Archives of disease in childhood 2011-06, Vol.96 (6), p.554-559 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 559 |
|---|---|
| container_issue | 6 |
| container_start_page | 554 |
| container_title | Archives of disease in childhood |
| container_volume | 96 |
| creator | Villa, Fabiane Castro, Ana Paula Beltran Moschione Pastorino, Antonio Carlos Santarém, José Maria Martins, Milton Arruda Jacob, Cristina Miuki Abe Carvalho, Celso Ricardo |
| description | Background Peripheral muscle strength and endurance are decreased in patients with chronic pulmonary diseases and seem to contribute to patients' exercise intolerance. However, the authors are not aware of any studies evaluating peripheral muscle function in children with asthma. It seems to be implied that children with asthma have lower aerobic fitness, but there are limited studies comparing the aerobic capacity of children with and without asthma. The present study aimed to evaluate muscle strength and endurance in children with persistent asthma and their association with aerobic capacity and inhaled corticosteroid consumption. Methods Forty children with mild persistent asthma (MPA) or severe persistent asthma (SPA) (N=20 each) and 20 children without asthma (control group) were evaluated. Upper (pectoralis and latissimus dorsi) and lower (quadriceps) muscle strength and endurance were assessed, and cardiopulmonary exercise testing was performed. Inhaled corticosteroid consumption during the last 6 and 24 months was also quantified. Results Children with SPA presented a reduction in peak oxygen consumption (VO2) (28.2±8.1 vs 34.7±6.9 ml/kg/min; p0.05). Finally, the authors observed that lower muscle endurance weakness was not associated with reductions in either peak VO2 (r=0.22, p>0.05) or corticosteroid consumption (r=−0.31, p>0.05) in children with asthma. Conclusion The findings suggest that cardiopulmonary exercise and lower limb muscle endurance should be a priority during physical training programs for children with severe asthma. |
| doi_str_mv | 10.1136/adc.2011.212431 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_866530327</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A259633411</galeid><sourcerecordid>A259633411</sourcerecordid><originalsourceid>FETCH-LOGICAL-b465t-5241f251f9511b3a62403cec9e848f3e22363adad5463dd39998ebbde0e8ff773</originalsourceid><addsrcrecordid>eNqFkU1v1DAQQC0EosvCmRuKhBASUrb-jn1cRS1fFb0AV8txJl1vnWRrJ4L-e7zK0kpcOM1hnq2neQi9JnhDCJPntnUbignZUEI5I0_QinCpSoo5f4pWGGNWaqXUGXqR0h5jQpViz9EZJZxqXckVuthCHBvvCmcP1vnpvrBDW6RbCDDZUPRzcgGKbh7c5Meh8EPhdj60EYbil592hU3Trrcv0bPOhgSvTnONflxefK8_lVfXHz_X26uy4VJMpaCcdFSQTgtCGmYl5Zg5cBoUVx0DSplktrWt4JK1LdNaK2iaFjCorqsqtkbvl38PcbybIU2m98lBCHaAcU5GSSkYZvRIvv2H3I9zHLKcISpfAQspdabKhbqxAYwf3DhM8HtyYwhwAya719dmS4WWjPF88DU6X3gXx5QidOYQfW_jvSHYHIOYHMQcg5glSH7x5uQxNz20D_zfAhl4dwJscjZ00Q7Op0eOU1xRSR5VfcqKD3sbb42sWCXMt5-1-VpXQosv3Fxm_sPCN_3-v5Z_AD4PrHE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1828805669</pqid></control><display><type>article</type><title>Aerobic capacity and skeletal muscle function in children with asthma</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><creator>Villa, Fabiane ; Castro, Ana Paula Beltran Moschione ; Pastorino, Antonio Carlos ; Santarém, José Maria ; Martins, Milton Arruda ; Jacob, Cristina Miuki Abe ; Carvalho, Celso Ricardo</creator><creatorcontrib>Villa, Fabiane ; Castro, Ana Paula Beltran Moschione ; Pastorino, Antonio Carlos ; Santarém, José Maria ; Martins, Milton Arruda ; Jacob, Cristina Miuki Abe ; Carvalho, Celso Ricardo</creatorcontrib><description>Background Peripheral muscle strength and endurance are decreased in patients with chronic pulmonary diseases and seem to contribute to patients' exercise intolerance. However, the authors are not aware of any studies evaluating peripheral muscle function in children with asthma. It seems to be implied that children with asthma have lower aerobic fitness, but there are limited studies comparing the aerobic capacity of children with and without asthma. The present study aimed to evaluate muscle strength and endurance in children with persistent asthma and their association with aerobic capacity and inhaled corticosteroid consumption. Methods Forty children with mild persistent asthma (MPA) or severe persistent asthma (SPA) (N=20 each) and 20 children without asthma (control group) were evaluated. Upper (pectoralis and latissimus dorsi) and lower (quadriceps) muscle strength and endurance were assessed, and cardiopulmonary exercise testing was performed. Inhaled corticosteroid consumption during the last 6 and 24 months was also quantified. Results Children with SPA presented a reduction in peak oxygen consumption (VO2) (28.2±8.1 vs 34.7±6.9 ml/kg/min; p<0.01) and quadriceps endurance (43.1±6.7 vs 80.9±11.9 repetitions; p<0.05) compared with the control group, but not the MPA group (31.5±6.1 ml/kg/min and 56.7±47.7 repetitions respectively; p>0.05). Maximal upper and lower muscle strength was preserved in children with both mild and severe asthma (p>0.05). Finally, the authors observed that lower muscle endurance weakness was not associated with reductions in either peak VO2 (r=0.22, p>0.05) or corticosteroid consumption (r=−0.31, p>0.05) in children with asthma. Conclusion The findings suggest that cardiopulmonary exercise and lower limb muscle endurance should be a priority during physical training programs for children with severe asthma.</description><identifier>ISSN: 0003-9888</identifier><identifier>EISSN: 1468-2044</identifier><identifier>DOI: 10.1136/adc.2011.212431</identifier><identifier>PMID: 21429976</identifier><identifier>CODEN: ADCHAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</publisher><subject>Adolescent ; Aerobics ; Airway management ; Anthropometry - methods ; Asthma ; Asthma - drug therapy ; Asthma - physiopathology ; Asthma in children ; Biological and medical sciences ; Care and treatment ; Case-Control Studies ; Child ; Childhood asthma ; Children & youth ; Chronic obstructive pulmonary disease ; Chronic obstructive pulmonary disease, asthma ; Control Groups ; Drug Administration Schedule ; Endurance ; Exercise ; Exercise - physiology ; Exercise Test - methods ; Exercise therapy ; Forced Expiratory Volume - physiology ; General aspects ; Glucocorticoids - administration & dosage ; Health aspects ; Humans ; Maximum oxygen consumption ; Medical sciences ; Methods ; Miscellaneous ; Muscle function ; Muscle strength ; Muscle Strength - physiology ; Muscle, Skeletal - physiopathology ; Muscular Strength ; Oxygen consumption ; Oxygen Consumption - physiology ; Physical Endurance - physiology ; Physical fitness ; Physical training ; Pneumology ; Prevention and actions ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Quality of life ; Range of motion ; Spirometry ; Spirometry - methods ; Steroids ; Strengthening exercises ; Vital Capacity - physiology ; Warm up (exercise)</subject><ispartof>Archives of disease in childhood, 2011-06, Vol.96 (6), p.554-559</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2011 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b465t-5241f251f9511b3a62403cec9e848f3e22363adad5463dd39998ebbde0e8ff773</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://adc.bmj.com/content/96/6/554.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://adc.bmj.com/content/96/6/554.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,314,776,780,3183,23552,27903,27904,77346,77377</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24207261$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21429976$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Villa, Fabiane</creatorcontrib><creatorcontrib>Castro, Ana Paula Beltran Moschione</creatorcontrib><creatorcontrib>Pastorino, Antonio Carlos</creatorcontrib><creatorcontrib>Santarém, José Maria</creatorcontrib><creatorcontrib>Martins, Milton Arruda</creatorcontrib><creatorcontrib>Jacob, Cristina Miuki Abe</creatorcontrib><creatorcontrib>Carvalho, Celso Ricardo</creatorcontrib><title>Aerobic capacity and skeletal muscle function in children with asthma</title><title>Archives of disease in childhood</title><addtitle>Arch Dis Child</addtitle><description>Background Peripheral muscle strength and endurance are decreased in patients with chronic pulmonary diseases and seem to contribute to patients' exercise intolerance. However, the authors are not aware of any studies evaluating peripheral muscle function in children with asthma. It seems to be implied that children with asthma have lower aerobic fitness, but there are limited studies comparing the aerobic capacity of children with and without asthma. The present study aimed to evaluate muscle strength and endurance in children with persistent asthma and their association with aerobic capacity and inhaled corticosteroid consumption. Methods Forty children with mild persistent asthma (MPA) or severe persistent asthma (SPA) (N=20 each) and 20 children without asthma (control group) were evaluated. Upper (pectoralis and latissimus dorsi) and lower (quadriceps) muscle strength and endurance were assessed, and cardiopulmonary exercise testing was performed. Inhaled corticosteroid consumption during the last 6 and 24 months was also quantified. Results Children with SPA presented a reduction in peak oxygen consumption (VO2) (28.2±8.1 vs 34.7±6.9 ml/kg/min; p<0.01) and quadriceps endurance (43.1±6.7 vs 80.9±11.9 repetitions; p<0.05) compared with the control group, but not the MPA group (31.5±6.1 ml/kg/min and 56.7±47.7 repetitions respectively; p>0.05). Maximal upper and lower muscle strength was preserved in children with both mild and severe asthma (p>0.05). Finally, the authors observed that lower muscle endurance weakness was not associated with reductions in either peak VO2 (r=0.22, p>0.05) or corticosteroid consumption (r=−0.31, p>0.05) in children with asthma. Conclusion The findings suggest that cardiopulmonary exercise and lower limb muscle endurance should be a priority during physical training programs for children with severe asthma.</description><subject>Adolescent</subject><subject>Aerobics</subject><subject>Airway management</subject><subject>Anthropometry - methods</subject><subject>Asthma</subject><subject>Asthma - drug therapy</subject><subject>Asthma - physiopathology</subject><subject>Asthma in children</subject><subject>Biological and medical sciences</subject><subject>Care and treatment</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Childhood asthma</subject><subject>Children & youth</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>Control Groups</subject><subject>Drug Administration Schedule</subject><subject>Endurance</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Exercise Test - methods</subject><subject>Exercise therapy</subject><subject>Forced Expiratory Volume - physiology</subject><subject>General aspects</subject><subject>Glucocorticoids - administration & dosage</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Maximum oxygen consumption</subject><subject>Medical sciences</subject><subject>Methods</subject><subject>Miscellaneous</subject><subject>Muscle function</subject><subject>Muscle strength</subject><subject>Muscle Strength - physiology</subject><subject>Muscle, Skeletal - physiopathology</subject><subject>Muscular Strength</subject><subject>Oxygen consumption</subject><subject>Oxygen Consumption - physiology</subject><subject>Physical Endurance - physiology</subject><subject>Physical fitness</subject><subject>Physical training</subject><subject>Pneumology</subject><subject>Prevention and actions</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Quality of life</subject><subject>Range of motion</subject><subject>Spirometry</subject><subject>Spirometry - methods</subject><subject>Steroids</subject><subject>Strengthening exercises</subject><subject>Vital Capacity - physiology</subject><subject>Warm up (exercise)</subject><issn>0003-9888</issn><issn>1468-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1v1DAQQC0EosvCmRuKhBASUrb-jn1cRS1fFb0AV8txJl1vnWRrJ4L-e7zK0kpcOM1hnq2neQi9JnhDCJPntnUbignZUEI5I0_QinCpSoo5f4pWGGNWaqXUGXqR0h5jQpViz9EZJZxqXckVuthCHBvvCmcP1vnpvrBDW6RbCDDZUPRzcgGKbh7c5Meh8EPhdj60EYbil592hU3Trrcv0bPOhgSvTnONflxefK8_lVfXHz_X26uy4VJMpaCcdFSQTgtCGmYl5Zg5cBoUVx0DSplktrWt4JK1LdNaK2iaFjCorqsqtkbvl38PcbybIU2m98lBCHaAcU5GSSkYZvRIvv2H3I9zHLKcISpfAQspdabKhbqxAYwf3DhM8HtyYwhwAya719dmS4WWjPF88DU6X3gXx5QidOYQfW_jvSHYHIOYHMQcg5glSH7x5uQxNz20D_zfAhl4dwJscjZ00Q7Op0eOU1xRSR5VfcqKD3sbb42sWCXMt5-1-VpXQosv3Fxm_sPCN_3-v5Z_AD4PrHE</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Villa, Fabiane</creator><creator>Castro, Ana Paula Beltran Moschione</creator><creator>Pastorino, Antonio Carlos</creator><creator>Santarém, José Maria</creator><creator>Martins, Milton Arruda</creator><creator>Jacob, Cristina Miuki Abe</creator><creator>Carvalho, Celso Ricardo</creator><general>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</general><general>BMJ Publishing Group</general><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88B</scope><scope>88E</scope><scope>88I</scope><scope>8A4</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>CJNVE</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>LK8</scope><scope>M0P</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEDU</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20110601</creationdate><title>Aerobic capacity and skeletal muscle function in children with asthma</title><author>Villa, Fabiane ; Castro, Ana Paula Beltran Moschione ; Pastorino, Antonio Carlos ; Santarém, José Maria ; Martins, Milton Arruda ; Jacob, Cristina Miuki Abe ; Carvalho, Celso Ricardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b465t-5241f251f9511b3a62403cec9e848f3e22363adad5463dd39998ebbde0e8ff773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Aerobics</topic><topic>Airway management</topic><topic>Anthropometry - methods</topic><topic>Asthma</topic><topic>Asthma - drug therapy</topic><topic>Asthma - physiopathology</topic><topic>Asthma in children</topic><topic>Biological and medical sciences</topic><topic>Care and treatment</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Childhood asthma</topic><topic>Children & youth</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>Control Groups</topic><topic>Drug Administration Schedule</topic><topic>Endurance</topic><topic>Exercise</topic><topic>Exercise - physiology</topic><topic>Exercise Test - methods</topic><topic>Exercise therapy</topic><topic>Forced Expiratory Volume - physiology</topic><topic>General aspects</topic><topic>Glucocorticoids - administration & dosage</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Maximum oxygen consumption</topic><topic>Medical sciences</topic><topic>Methods</topic><topic>Miscellaneous</topic><topic>Muscle function</topic><topic>Muscle strength</topic><topic>Muscle Strength - physiology</topic><topic>Muscle, Skeletal - physiopathology</topic><topic>Muscular Strength</topic><topic>Oxygen consumption</topic><topic>Oxygen Consumption - physiology</topic><topic>Physical Endurance - physiology</topic><topic>Physical fitness</topic><topic>Physical training</topic><topic>Pneumology</topic><topic>Prevention and actions</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Quality of life</topic><topic>Range of motion</topic><topic>Spirometry</topic><topic>Spirometry - methods</topic><topic>Steroids</topic><topic>Strengthening exercises</topic><topic>Vital Capacity - physiology</topic><topic>Warm up (exercise)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Villa, Fabiane</creatorcontrib><creatorcontrib>Castro, Ana Paula Beltran Moschione</creatorcontrib><creatorcontrib>Pastorino, Antonio Carlos</creatorcontrib><creatorcontrib>Santarém, José Maria</creatorcontrib><creatorcontrib>Martins, Milton Arruda</creatorcontrib><creatorcontrib>Jacob, Cristina Miuki Abe</creatorcontrib><creatorcontrib>Carvalho, Celso Ricardo</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection【Remote access available】</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Education Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Education Periodicals</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>Social Science Premium Collection</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Education Collection</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Education Database</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>ProQuest One Education</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of disease in childhood</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Villa, Fabiane</au><au>Castro, Ana Paula Beltran Moschione</au><au>Pastorino, Antonio Carlos</au><au>Santarém, José Maria</au><au>Martins, Milton Arruda</au><au>Jacob, Cristina Miuki Abe</au><au>Carvalho, Celso Ricardo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aerobic capacity and skeletal muscle function in children with asthma</atitle><jtitle>Archives of disease in childhood</jtitle><addtitle>Arch Dis Child</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>96</volume><issue>6</issue><spage>554</spage><epage>559</epage><pages>554-559</pages><issn>0003-9888</issn><eissn>1468-2044</eissn><coden>ADCHAK</coden><abstract>Background Peripheral muscle strength and endurance are decreased in patients with chronic pulmonary diseases and seem to contribute to patients' exercise intolerance. However, the authors are not aware of any studies evaluating peripheral muscle function in children with asthma. It seems to be implied that children with asthma have lower aerobic fitness, but there are limited studies comparing the aerobic capacity of children with and without asthma. The present study aimed to evaluate muscle strength and endurance in children with persistent asthma and their association with aerobic capacity and inhaled corticosteroid consumption. Methods Forty children with mild persistent asthma (MPA) or severe persistent asthma (SPA) (N=20 each) and 20 children without asthma (control group) were evaluated. Upper (pectoralis and latissimus dorsi) and lower (quadriceps) muscle strength and endurance were assessed, and cardiopulmonary exercise testing was performed. Inhaled corticosteroid consumption during the last 6 and 24 months was also quantified. Results Children with SPA presented a reduction in peak oxygen consumption (VO2) (28.2±8.1 vs 34.7±6.9 ml/kg/min; p<0.01) and quadriceps endurance (43.1±6.7 vs 80.9±11.9 repetitions; p<0.05) compared with the control group, but not the MPA group (31.5±6.1 ml/kg/min and 56.7±47.7 repetitions respectively; p>0.05). Maximal upper and lower muscle strength was preserved in children with both mild and severe asthma (p>0.05). Finally, the authors observed that lower muscle endurance weakness was not associated with reductions in either peak VO2 (r=0.22, p>0.05) or corticosteroid consumption (r=−0.31, p>0.05) in children with asthma. Conclusion The findings suggest that cardiopulmonary exercise and lower limb muscle endurance should be a priority during physical training programs for children with severe asthma.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health</pub><pmid>21429976</pmid><doi>10.1136/adc.2011.212431</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-9888 |
| ispartof | Archives of disease in childhood, 2011-06, Vol.96 (6), p.554-559 |
| issn | 0003-9888 1468-2044 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_866530327 |
| source | MEDLINE; BMJ Journals - NESLi2 |
| subjects | Adolescent Aerobics Airway management Anthropometry - methods Asthma Asthma - drug therapy Asthma - physiopathology Asthma in children Biological and medical sciences Care and treatment Case-Control Studies Child Childhood asthma Children & youth Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease, asthma Control Groups Drug Administration Schedule Endurance Exercise Exercise - physiology Exercise Test - methods Exercise therapy Forced Expiratory Volume - physiology General aspects Glucocorticoids - administration & dosage Health aspects Humans Maximum oxygen consumption Medical sciences Methods Miscellaneous Muscle function Muscle strength Muscle Strength - physiology Muscle, Skeletal - physiopathology Muscular Strength Oxygen consumption Oxygen Consumption - physiology Physical Endurance - physiology Physical fitness Physical training Pneumology Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Quality of life Range of motion Spirometry Spirometry - methods Steroids Strengthening exercises Vital Capacity - physiology Warm up (exercise) |
| title | Aerobic capacity and skeletal muscle function in children with asthma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T21%3A25%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Aerobic%20capacity%20and%20skeletal%20muscle%20function%20in%20children%20with%20asthma&rft.jtitle=Archives%20of%20disease%20in%20childhood&rft.au=Villa,%20Fabiane&rft.date=2011-06-01&rft.volume=96&rft.issue=6&rft.spage=554&rft.epage=559&rft.pages=554-559&rft.issn=0003-9888&rft.eissn=1468-2044&rft.coden=ADCHAK&rft_id=info:doi/10.1136/adc.2011.212431&rft_dat=%3Cgale_proqu%3EA259633411%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1828805669&rft_id=info:pmid/21429976&rft_galeid=A259633411&rfr_iscdi=true |