Efficient algorithms for the discovery of DNA oligonucleotide barcodes from sequence databases

Efficient design of barcode oligonucleotides can lead to significant cost reductions in the manufacturing of DNA arrays. Previous methods are based on either a preliminary alignment, which reduces their efficiency for intron-rich regions, or on a brute force approach, not feasible for large-scale pr...

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Veröffentlicht in:	Molecular ecology 2009-05, Vol.9 (s1), p.58-64
Hauptverfasser:	ZAHARIEV, M, DAHL, V, CHEN, W, LÉVESQUE, C.A
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms array designer Genetic markers genotyping microarray Mitochondrial DNA Molecular biology reverse dot blot hybridization SigOli single nucleotide polymorphism (SNP)
Online-Zugang:	Volltext
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