Inhibition of excitatory synaptic transmission in the trigeminal motor nucleus by the nitric oxide-cyclic GMP signaling pathway

Nitric oxide (NO) and cyclic GMP (cGMP) suppressed glutamatergic synaptic transmission to trigeminal motoneurons in brain stem slices of neonatal rats. Histological studies showed guanylate cyclase (GC) containing fibers in the trigeminal motor pool. Glutamatergic excitatory postsynaptic currents (E...

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Veröffentlicht in:	Brain research 2011-06, Vol.1393, p.1-16
Hauptverfasser:	Pose, Inés, Silveira, Valentina, Morales, Francisco R
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Animals, Newborn Cyclic GMP - analogs & derivatives Cyclic GMP - metabolism Cyclic GMP - pharmacology Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Glutamic Acid - physiology Motor Neurons - drug effects Motor Neurons - physiology Neural Inhibition - drug effects Neural Inhibition - physiology Nitric Oxide - metabolism Nitric Oxide Donors - pharmacology Organ Culture Techniques Presynaptic Terminals - physiology Rats Rats, Wistar Signal Transduction - drug effects Signal Transduction - physiology Triazenes - pharmacology Trigeminal Nuclei - cytology Trigeminal Nuclei - physiology
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