Role of computed tomography in the evaluation of pediatric brain tumor
A total of forty two clinically diagnosed pediatric brain tumors were studied over a period of two years. The study was aimed to evaluate the efficacy of computed tomography (CT) in pre-operative diagnosis of pediatric brain tumors by correlating the imaging findings with postoperative histopatholog...
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Veröffentlicht in: | Bangladesh Medical Research Council bulletin 2010-12, Vol.36 (3), p.89-92 |
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creator | Haque, Md Ziaul Karim, Md Enayet Al-Azad, Salahuddin Mahmood-uz-jahan |
description | A total of forty two clinically diagnosed pediatric brain tumors were studied over a period of two years. The study was aimed to evaluate the efficacy of computed tomography (CT) in pre-operative diagnosis of pediatric brain tumors by correlating the imaging findings with postoperative histopathological findings. Site, density, mass effect and contrast enhancement of the lesion were studied as primary efficacy variables of CT scan. In the present study, the common pediatric brain tumors were astrocytoma, medulloblastoma, craniopharyngioma and ependymoma. In 18(42.9%) cases the tumors were supratentorial and in 24 (57.1%), they were infratentorial in location. The findings of CT scan in different intracranial neoplasm strongly correlated with those of histopathology. The validity tests for CT scan were found to be 88.9% sensitive, 100% specific and about 95% accurate in diagnosing astrocytoma. Similarly the sensitivity, specificity, and accuracy for medulloblastoma were 100%, 96.9% and 97.7% respectively. For craniopharyngioma the values were 85.7%, 100% and 97.7% respectively. The study concludes that CT is an invaluable imaging modality in preoperative diagnosis of pediatric brain tumor due to its excellent characterization of tumors. |
doi_str_mv | 10.3329/bmrcb.v36i3.7288 |
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The study was aimed to evaluate the efficacy of computed tomography (CT) in pre-operative diagnosis of pediatric brain tumors by correlating the imaging findings with postoperative histopathological findings. Site, density, mass effect and contrast enhancement of the lesion were studied as primary efficacy variables of CT scan. In the present study, the common pediatric brain tumors were astrocytoma, medulloblastoma, craniopharyngioma and ependymoma. In 18(42.9%) cases the tumors were supratentorial and in 24 (57.1%), they were infratentorial in location. The findings of CT scan in different intracranial neoplasm strongly correlated with those of histopathology. The validity tests for CT scan were found to be 88.9% sensitive, 100% specific and about 95% accurate in diagnosing astrocytoma. Similarly the sensitivity, specificity, and accuracy for medulloblastoma were 100%, 96.9% and 97.7% respectively. For craniopharyngioma the values were 85.7%, 100% and 97.7% respectively. The study concludes that CT is an invaluable imaging modality in preoperative diagnosis of pediatric brain tumor due to its excellent characterization of tumors.</description><identifier>ISSN: 0377-9238</identifier><identifier>EISSN: 2224-7238</identifier><identifier>DOI: 10.3329/bmrcb.v36i3.7288</identifier><identifier>PMID: 21548545</identifier><language>eng</language><publisher>Bangladesh</publisher><subject>Adolescent ; Brain Neoplasms - diagnostic imaging ; Brain Neoplasms - pathology ; Child ; Child, Preschool ; Female ; Humans ; Male ; Sensitivity and Specificity ; Tomography, X-Ray Computed</subject><ispartof>Bangladesh Medical Research Council bulletin, 2010-12, Vol.36 (3), p.89-92</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4122,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21548545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Haque, Md Ziaul</creatorcontrib><creatorcontrib>Karim, Md Enayet</creatorcontrib><creatorcontrib>Al-Azad, Salahuddin</creatorcontrib><creatorcontrib>Mahmood-uz-jahan</creatorcontrib><title>Role of computed tomography in the evaluation of pediatric brain tumor</title><title>Bangladesh Medical Research Council bulletin</title><addtitle>Bangladesh Med Res Counc Bull</addtitle><description>A total of forty two clinically diagnosed pediatric brain tumors were studied over a period of two years. The study was aimed to evaluate the efficacy of computed tomography (CT) in pre-operative diagnosis of pediatric brain tumors by correlating the imaging findings with postoperative histopathological findings. Site, density, mass effect and contrast enhancement of the lesion were studied as primary efficacy variables of CT scan. In the present study, the common pediatric brain tumors were astrocytoma, medulloblastoma, craniopharyngioma and ependymoma. In 18(42.9%) cases the tumors were supratentorial and in 24 (57.1%), they were infratentorial in location. The findings of CT scan in different intracranial neoplasm strongly correlated with those of histopathology. The validity tests for CT scan were found to be 88.9% sensitive, 100% specific and about 95% accurate in diagnosing astrocytoma. Similarly the sensitivity, specificity, and accuracy for medulloblastoma were 100%, 96.9% and 97.7% respectively. For craniopharyngioma the values were 85.7%, 100% and 97.7% respectively. The study concludes that CT is an invaluable imaging modality in preoperative diagnosis of pediatric brain tumor due to its excellent characterization of tumors.</description><subject>Adolescent</subject><subject>Brain Neoplasms - diagnostic imaging</subject><subject>Brain Neoplasms - pathology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, X-Ray Computed</subject><issn>0377-9238</issn><issn>2224-7238</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kN9LwzAQx4Morsy9-yR986kzP5o2fZThVBgIos8hSa8u0i41aQf770236b3cwX2-x_FB6JbgJWO0etCdN3q5Z4Vly5IKcYESSmmelZSJS5RgVpZZFecZWoTwjWPFFOPsGs0o4bngOU_Q-t21kLomNa7rxwHqdHCd-_Kq3x5Su0uHLaSwV-2oBut2E9hDbdXgrUm1VxMxds7foKtGtQEW5z5Hn-unj9VLtnl7fl09bjJDimLINCbAFVENVCSvqNB1ibUoFRfxOaY5ZVzlwhAu8qapc2qqCmpcG9Cm0XHD5uj-dLf37meEMMjOBgNtq3bgxiBFwYuqYBRHEp9I410IHhrZe9spf5AEy8mfPPqTR39y8hcjd-fjo-6g_g_82WK_hxZtsQ</recordid><startdate>201012</startdate><enddate>201012</enddate><creator>Haque, Md Ziaul</creator><creator>Karim, Md Enayet</creator><creator>Al-Azad, Salahuddin</creator><creator>Mahmood-uz-jahan</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201012</creationdate><title>Role of computed tomography in the evaluation of pediatric brain tumor</title><author>Haque, Md Ziaul ; Karim, Md Enayet ; Al-Azad, Salahuddin ; Mahmood-uz-jahan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c166t-b01e5a1afe914928bd70b87a580033b5235a48c1584ffd42c99ed0dcebcfba483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adolescent</topic><topic>Brain Neoplasms - diagnostic imaging</topic><topic>Brain Neoplasms - pathology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Sensitivity and Specificity</topic><topic>Tomography, X-Ray Computed</topic><toplevel>online_resources</toplevel><creatorcontrib>Haque, Md Ziaul</creatorcontrib><creatorcontrib>Karim, Md Enayet</creatorcontrib><creatorcontrib>Al-Azad, Salahuddin</creatorcontrib><creatorcontrib>Mahmood-uz-jahan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bangladesh Medical Research Council bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Haque, Md Ziaul</au><au>Karim, Md Enayet</au><au>Al-Azad, Salahuddin</au><au>Mahmood-uz-jahan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of computed tomography in the evaluation of pediatric brain tumor</atitle><jtitle>Bangladesh Medical Research Council bulletin</jtitle><addtitle>Bangladesh Med Res Counc Bull</addtitle><date>2010-12</date><risdate>2010</risdate><volume>36</volume><issue>3</issue><spage>89</spage><epage>92</epage><pages>89-92</pages><issn>0377-9238</issn><eissn>2224-7238</eissn><abstract>A total of forty two clinically diagnosed pediatric brain tumors were studied over a period of two years. The study was aimed to evaluate the efficacy of computed tomography (CT) in pre-operative diagnosis of pediatric brain tumors by correlating the imaging findings with postoperative histopathological findings. Site, density, mass effect and contrast enhancement of the lesion were studied as primary efficacy variables of CT scan. In the present study, the common pediatric brain tumors were astrocytoma, medulloblastoma, craniopharyngioma and ependymoma. In 18(42.9%) cases the tumors were supratentorial and in 24 (57.1%), they were infratentorial in location. The findings of CT scan in different intracranial neoplasm strongly correlated with those of histopathology. The validity tests for CT scan were found to be 88.9% sensitive, 100% specific and about 95% accurate in diagnosing astrocytoma. Similarly the sensitivity, specificity, and accuracy for medulloblastoma were 100%, 96.9% and 97.7% respectively. For craniopharyngioma the values were 85.7%, 100% and 97.7% respectively. 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source | MEDLINE; Bangladesh Journals Online; EZB-FREE-00999 freely available EZB journals |
subjects | Adolescent Brain Neoplasms - diagnostic imaging Brain Neoplasms - pathology Child Child, Preschool Female Humans Male Sensitivity and Specificity Tomography, X-Ray Computed |
title | Role of computed tomography in the evaluation of pediatric brain tumor |
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