Characterization of a Lipophilic Plasmid DNA Condensate Formed with a Cationic Peptide Fatty Acid Conjugate

In the presence of cationic ligands, DNA molecules can become aggregated into larger particles in a process known as condensation. DNA condensates are of interest as models for the dense packing found in naturally occurring structures such as phage heads and chromatin. They have found extensive appl...

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Veröffentlicht in:	Biomacromolecules 2011-05, Vol.12 (5), p.1731-1737
Hauptverfasser:	Do, Trinh T, Tang, Vicky J, Aguilera, Joe A, Perry, Christopher C, Milligan, Jamie R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cations Circular Dichroism Diverse techniques DNA - chemistry Electrophoresis, Agar Gel Fatty Acids - chemistry Fundamental and applied biological sciences. Psychology Ligands Molecular and cellular biology Peptides - chemistry Plasmids Spectrophotometry, Ultraviolet
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