Placental oxidative DNA damage and its repair in preeclamptic women with fetal growth restriction

Abstract Preeclampsia is frequently accompanied by fetal growth restriction (FGR). Preeclampsia increases oxygen free radical production, and the resulting oxidative stress impairs placental blood flow. To determine whether placental oxidative stress is associated with FGR in preeclamptic women, we...

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Veröffentlicht in:	Placenta (Eastbourne) 2011-05, Vol.32 (5), p.367-372
Hauptverfasser:	Fujimaki, A, Watanabe, K, Mori, T, Kimura, C, Shinohara, K, Wakatsuki, A
Format:	Artikel
Sprache:	eng
Schlagworte:	8-OHdG Adult Biological and medical sciences Case-Control Studies Deoxyguanosine - analogs & derivatives Deoxyguanosine - metabolism DNA Damage DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism Embryology: invertebrates and vertebrates. Teratology Female Fetal Blood - metabolism Fetal Growth Retardation - metabolism FGR Free Radicals - blood Fundamental and applied biological sciences. Psychology Humans Internal Medicine Obstetrics and Gynecology Oxidative Stress Oxygen - blood Placenta - metabolism Pre-Eclampsia - metabolism Preeclampsia Pregnancy Ref-1
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