Black bone disease of the foot. Minocycline related pigmentation
Abstract Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycl...
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Veröffentlicht in: | Foot and ankle surgery 2011-06, Vol.17 (2), p.e34-e36 |
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container_title | Foot and ankle surgery |
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creator | Middleton, S.D., MBChB Anakwe, R.E., FRCS(Orth) McKinley, J.C., BMSc(Hons), FRCS(Orth) |
description | Abstract Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycline use. The unique features of this case relate to the location of the discolouration and the normal physical properties of the bone and soft tissues at surgery despite heavy pigmentation. Healing is now complete and follow-up at two years confirmed excellent clinical and radiological outcomes. |
doi_str_mv | 10.1016/j.fas.2011.01.011 |
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Minocycline related pigmentation</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Middleton, S.D., MBChB ; Anakwe, R.E., FRCS(Orth) ; McKinley, J.C., BMSc(Hons), FRCS(Orth)</creator><creatorcontrib>Middleton, S.D., MBChB ; Anakwe, R.E., FRCS(Orth) ; McKinley, J.C., BMSc(Hons), FRCS(Orth)</creatorcontrib><description>Abstract Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycline use. The unique features of this case relate to the location of the discolouration and the normal physical properties of the bone and soft tissues at surgery despite heavy pigmentation. Healing is now complete and follow-up at two years confirmed excellent clinical and radiological outcomes.</description><identifier>ISSN: 1268-7731</identifier><identifier>EISSN: 1460-9584</identifier><identifier>DOI: 10.1016/j.fas.2011.01.011</identifier><identifier>PMID: 21549970</identifier><language>eng</language><publisher>France: Elsevier Ltd</publisher><subject>Anti-Bacterial Agents - adverse effects ; Black bone disease ; Bone Diseases - chemically induced ; Female ; Foot ; Hallux Valgus - surgery ; Humans ; Hyperpigmentation - chemically induced ; Incidental Findings ; Metatarsal Bones - pathology ; Middle Aged ; Minocycline ; Minocycline - adverse effects ; Orthopedics ; Pigmentation ; Toe Phalanges - pathology</subject><ispartof>Foot and ankle surgery, 2011-06, Vol.17 (2), p.e34-e36</ispartof><rights>European Foot and Ankle Society</rights><rights>2011 European Foot and Ankle Society</rights><rights>Copyright © 2011 European Foot and Ankle Society. 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Minocycline related pigmentation</title><title>Foot and ankle surgery</title><addtitle>Foot Ankle Surg</addtitle><description>Abstract Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycline use. The unique features of this case relate to the location of the discolouration and the normal physical properties of the bone and soft tissues at surgery despite heavy pigmentation. Healing is now complete and follow-up at two years confirmed excellent clinical and radiological outcomes.</description><subject>Anti-Bacterial Agents - adverse effects</subject><subject>Black bone disease</subject><subject>Bone Diseases - chemically induced</subject><subject>Female</subject><subject>Foot</subject><subject>Hallux Valgus - surgery</subject><subject>Humans</subject><subject>Hyperpigmentation - chemically induced</subject><subject>Incidental Findings</subject><subject>Metatarsal Bones - pathology</subject><subject>Middle Aged</subject><subject>Minocycline</subject><subject>Minocycline - adverse effects</subject><subject>Orthopedics</subject><subject>Pigmentation</subject><subject>Toe Phalanges - pathology</subject><issn>1268-7731</issn><issn>1460-9584</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU9r3DAUxEVoaP60HyCX4FtPdt-TbMkmEJqEpgmk9ND2LGT5qdXGa20lb2C_fWU26aGHwIAkmBnQbxg7Q6gQUH5cVc6kigNiBYvwgB1jLaHsmrZ-k-9ctqVSAo_YSUorAFAdiLfsiGNTd52CY_bpejT2sejDRMXgE5lERXDF_JsKF8JcFV_9FOzOjj4bIo1mpqHY-F9rmmYz-zC9Y4fOjIneP5-n7Oft5x83d-XDty_3N1cPpRW1mkspoRVONSQGkIo74QRaY1QNde_I8qFXhnoxWJ6fUqqWEyAXPTUSnMFGnLIP-95NDH-2lGa99snSOJqJwjbpVjay7aRQ2Yl7p40hpUhOb6Jfm7jTCHrhplc6c9MLNw2LMGfOn9u3_ZqGf4kXUNlwsTdQ_uOTp6iT9TRZGnwkO-sh-FfrL_9LL0C9NeMj7SitwjZOGZ5GnbgG_X0ZbtkNMW8msv4CZu6R-Q</recordid><startdate>201106</startdate><enddate>201106</enddate><creator>Middleton, S.D., MBChB</creator><creator>Anakwe, R.E., FRCS(Orth)</creator><creator>McKinley, J.C., BMSc(Hons), FRCS(Orth)</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201106</creationdate><title>Black bone disease of the foot. 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Minocycline related pigmentation</atitle><jtitle>Foot and ankle surgery</jtitle><addtitle>Foot Ankle Surg</addtitle><date>2011-06</date><risdate>2011</risdate><volume>17</volume><issue>2</issue><spage>e34</spage><epage>e36</epage><pages>e34-e36</pages><issn>1268-7731</issn><eissn>1460-9584</eissn><abstract>Abstract Black bone disease is a rare manifestation of long term treatment with tetracyclines. We report the case of a patient who underwent surgery for bilateral hallux valgus and was found to have black discolouration of both first rays. This was subsequently related to previous long term Minocycline use. The unique features of this case relate to the location of the discolouration and the normal physical properties of the bone and soft tissues at surgery despite heavy pigmentation. Healing is now complete and follow-up at two years confirmed excellent clinical and radiological outcomes.</abstract><cop>France</cop><pub>Elsevier Ltd</pub><pmid>21549970</pmid><doi>10.1016/j.fas.2011.01.011</doi></addata></record> |
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subjects | Anti-Bacterial Agents - adverse effects Black bone disease Bone Diseases - chemically induced Female Foot Hallux Valgus - surgery Humans Hyperpigmentation - chemically induced Incidental Findings Metatarsal Bones - pathology Middle Aged Minocycline Minocycline - adverse effects Orthopedics Pigmentation Toe Phalanges - pathology |
title | Black bone disease of the foot. Minocycline related pigmentation |
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