Nonenhanced ECG-gated time-resolved 4D Steady-state free precession (SSFP) MR angiography (MRA) for assessment of cerebral collateral flow: comparison with digital subtraction angiography (DSA)

Objectives To evaluate a nonenhanced time-resolved 4D SSFP MRA for dynamic visualization of intracranial collateral blood flow. Methods 22 patients (59.0 ± 11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was a...

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Veröffentlicht in:European radiology 2011-06, Vol.21 (6), p.1329-1338
Hauptverfasser: Lanzman, Rotem Shlomo, Kröpil, Patric, Schmitt, Peter, Bi, Xiaoming, Gliem, Michael, Miese, Falk R., Hänggi, Daniel, Kamp, Marcel, Scherer, Axel, Turowski, Bernd, Blondin, Dirk
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container_end_page 1338
container_issue 6
container_start_page 1329
container_title European radiology
container_volume 21
creator Lanzman, Rotem Shlomo
Kröpil, Patric
Schmitt, Peter
Bi, Xiaoming
Gliem, Michael
Miese, Falk R.
Hänggi, Daniel
Kamp, Marcel
Scherer, Axel
Turowski, Bernd
Blondin, Dirk
description Objectives To evaluate a nonenhanced time-resolved 4D SSFP MRA for dynamic visualization of intracranial collateral blood flow. Methods 22 patients (59.0 ± 11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was acquired with 15 temporal phases and a temporal resolution of 115 ms using 1.5 T MR. Cerebral DSA served as the reference standard and was available in all patients. Results Nonenhanced 4D SSFP MRA allowed for detailed dynamic visualization of blood flow in the circle of Willis and its branches in 21 of 22 (95.5%) patients. Collateral flow was excluded with both 4D SSFP MRA and DSA in 4 patients. In 17 patients, DSA detected anterior collateral flow ( n  = 8), posterior collateral flow via the right ( n  = 8) and left ( n  = 7) posterior communicating artery as well as patent EC-IC bypasses ( n  = 8). 29 of 31 collateral flow pathways were visualized by 4D SSFP MRA. As compared to DSA, 4D SSFP MRA showed a high sensitivity (92.3%), specificity (100%), positive predictive value (100%) and negative predictive value (95.2%) for visualization of intracranial collateral flow. Conclusions 4D SSFP MRA is a promising non-invasive imaging technique for dynamic visualization of intracranial collateral flow.
doi_str_mv 10.1007/s00330-010-2051-9
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Methods 22 patients (59.0 ± 11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was acquired with 15 temporal phases and a temporal resolution of 115 ms using 1.5 T MR. Cerebral DSA served as the reference standard and was available in all patients. Results Nonenhanced 4D SSFP MRA allowed for detailed dynamic visualization of blood flow in the circle of Willis and its branches in 21 of 22 (95.5%) patients. Collateral flow was excluded with both 4D SSFP MRA and DSA in 4 patients. In 17 patients, DSA detected anterior collateral flow ( n  = 8), posterior collateral flow via the right ( n  = 8) and left ( n  = 7) posterior communicating artery as well as patent EC-IC bypasses ( n  = 8). 29 of 31 collateral flow pathways were visualized by 4D SSFP MRA. As compared to DSA, 4D SSFP MRA showed a high sensitivity (92.3%), specificity (100%), positive predictive value (100%) and negative predictive value (95.2%) for visualization of intracranial collateral flow. Conclusions 4D SSFP MRA is a promising non-invasive imaging technique for dynamic visualization of intracranial collateral flow.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-010-2051-9</identifier><identifier>PMID: 21225268</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Angiography, Digital Subtraction - methods ; Blood Flow Velocity ; Cardiac-Gated Imaging Techniques - methods ; Carotid arteries ; Cerebrovascular Circulation ; Circle of Willis - physiopathology ; Contrast agents ; Diagnostic Radiology ; Electrocardiography - methods ; Female ; Hemodynamics ; Hospitals ; Humans ; Image Enhancement ; Imaging ; Imaging, Three-Dimensional - methods ; Internal Medicine ; Interventional Radiology ; Magnetic Resonance Imaging - methods ; Male ; Medical imaging ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Neuroradiology ; Patients ; Radiology ; Reproducibility of Results ; Sensitivity and Specificity ; Ultrasound ; Vascular-Interventional ; Visualization</subject><ispartof>European radiology, 2011-06, Vol.21 (6), p.1329-1338</ispartof><rights>European Society of Radiology 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c370t-c66bfa8c1238e543b1a1748c6e940ccb70b786541453846444043b670b99415c3</citedby><cites>FETCH-LOGICAL-c370t-c66bfa8c1238e543b1a1748c6e940ccb70b786541453846444043b670b99415c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-010-2051-9$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-010-2051-9$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21225268$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lanzman, Rotem Shlomo</creatorcontrib><creatorcontrib>Kröpil, Patric</creatorcontrib><creatorcontrib>Schmitt, Peter</creatorcontrib><creatorcontrib>Bi, Xiaoming</creatorcontrib><creatorcontrib>Gliem, Michael</creatorcontrib><creatorcontrib>Miese, Falk R.</creatorcontrib><creatorcontrib>Hänggi, Daniel</creatorcontrib><creatorcontrib>Kamp, Marcel</creatorcontrib><creatorcontrib>Scherer, Axel</creatorcontrib><creatorcontrib>Turowski, Bernd</creatorcontrib><creatorcontrib>Blondin, Dirk</creatorcontrib><title>Nonenhanced ECG-gated time-resolved 4D Steady-state free precession (SSFP) MR angiography (MRA) for assessment of cerebral collateral flow: comparison with digital subtraction angiography (DSA)</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives To evaluate a nonenhanced time-resolved 4D SSFP MRA for dynamic visualization of intracranial collateral blood flow. Methods 22 patients (59.0 ± 11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was acquired with 15 temporal phases and a temporal resolution of 115 ms using 1.5 T MR. Cerebral DSA served as the reference standard and was available in all patients. Results Nonenhanced 4D SSFP MRA allowed for detailed dynamic visualization of blood flow in the circle of Willis and its branches in 21 of 22 (95.5%) patients. Collateral flow was excluded with both 4D SSFP MRA and DSA in 4 patients. In 17 patients, DSA detected anterior collateral flow ( n  = 8), posterior collateral flow via the right ( n  = 8) and left ( n  = 7) posterior communicating artery as well as patent EC-IC bypasses ( n  = 8). 29 of 31 collateral flow pathways were visualized by 4D SSFP MRA. As compared to DSA, 4D SSFP MRA showed a high sensitivity (92.3%), specificity (100%), positive predictive value (100%) and negative predictive value (95.2%) for visualization of intracranial collateral flow. 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Methods 22 patients (59.0 ± 11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was acquired with 15 temporal phases and a temporal resolution of 115 ms using 1.5 T MR. Cerebral DSA served as the reference standard and was available in all patients. Results Nonenhanced 4D SSFP MRA allowed for detailed dynamic visualization of blood flow in the circle of Willis and its branches in 21 of 22 (95.5%) patients. Collateral flow was excluded with both 4D SSFP MRA and DSA in 4 patients. In 17 patients, DSA detected anterior collateral flow ( n  = 8), posterior collateral flow via the right ( n  = 8) and left ( n  = 7) posterior communicating artery as well as patent EC-IC bypasses ( n  = 8). 29 of 31 collateral flow pathways were visualized by 4D SSFP MRA. As compared to DSA, 4D SSFP MRA showed a high sensitivity (92.3%), specificity (100%), positive predictive value (100%) and negative predictive value (95.2%) for visualization of intracranial collateral flow. Conclusions 4D SSFP MRA is a promising non-invasive imaging technique for dynamic visualization of intracranial collateral flow.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>21225268</pmid><doi>10.1007/s00330-010-2051-9</doi><tpages>10</tpages></addata></record>
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Angiography, Digital Subtraction - methods
Blood Flow Velocity
Cardiac-Gated Imaging Techniques - methods
Carotid arteries
Cerebrovascular Circulation
Circle of Willis - physiopathology
Contrast agents
Diagnostic Radiology
Electrocardiography - methods
Female
Hemodynamics
Hospitals
Humans
Image Enhancement
Imaging
Imaging, Three-Dimensional - methods
Internal Medicine
Interventional Radiology
Magnetic Resonance Imaging - methods
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Neuroradiology
Patients
Radiology
Reproducibility of Results
Sensitivity and Specificity
Ultrasound
Vascular-Interventional
Visualization
title Nonenhanced ECG-gated time-resolved 4D Steady-state free precession (SSFP) MR angiography (MRA) for assessment of cerebral collateral flow: comparison with digital subtraction angiography (DSA)
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