Spontaneous Crystalline-to-Amorphous Phase Transformation of Organic or Medicinal Compounds in the Presence of Porous Media, Part 1: Thermodynamics of Spontaneous Amorphization

Spontaneous crystalline-to-amorphous phase transformation of organic or medicinal molecules in the presence of mesoporous materials has been observed, for which pathway was suggested to be via the vapor phase, that is, sublimation of the crystalline molecules followed by adsorption on the porous med...

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Veröffentlicht in:Journal of pharmaceutical sciences 2011-07, Vol.100 (7), p.2801-2815
Hauptverfasser: Qian, Ken K., Bogner, Robin H.
Format: Artikel
Sprache:eng
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