Adrenalectomy for isolated adrenal metastasis after Gamma Knife Surgery for an intracerebral metastasis of non-small-cell lung carcinoma

Only a limited group of patients with non-small-cell lung cancer (NSCLC) is eligible for treatment with a curative intent. Adrenalectomy for a solitary adrenal metastasis of NSCLC may be curative when combined with resection of the primary tumor. It is unclear whether resection of an isolated adrena...

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Veröffentlicht in:Journal of cancer research and therapeutics 2011-01, Vol.7 (1), p.75-77
Hauptverfasser: van Uden, D.J.P, Ullmann, E.F, Reijnen, M.M.P.J
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container_title Journal of cancer research and therapeutics
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creator van Uden, D.J.P
Ullmann, E.F
Reijnen, M.M.P.J
description Only a limited group of patients with non-small-cell lung cancer (NSCLC) is eligible for treatment with a curative intent. Adrenalectomy for a solitary adrenal metastasis of NSCLC may be curative when combined with resection of the primary tumor. It is unclear whether resection of an isolated adrenal metastasis is justified in patients with a second metastasis. We report a case of successful adrenalectomy with adjuvant chemotherapy in a patient who was previously treated with a right lower lobe resection and subsequent Gamma Knife treatment of an intracranial metastasis. At 20-month follow-up, patient was in a good clinical condition without signs of recurrent disease. In selected cases, adrenalectomy with adjuvant chemotherapy for an adrenal metastasis of NSCLC may be performed successfully, with good short-term results, even after earlier treatment of a cerebral metastasis.
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Adrenalectomy for a solitary adrenal metastasis of NSCLC may be curative when combined with resection of the primary tumor. It is unclear whether resection of an isolated adrenal metastasis is justified in patients with a second metastasis. We report a case of successful adrenalectomy with adjuvant chemotherapy in a patient who was previously treated with a right lower lobe resection and subsequent Gamma Knife treatment of an intracranial metastasis. At 20-month follow-up, patient was in a good clinical condition without signs of recurrent disease. 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identifier ISSN: 0973-1482
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subjects Adrenal Gland Neoplasms - secondary
Adrenal Gland Neoplasms - surgery
Adrenal glands
Adrenalectomy
Adrenalectomy, chemotherapy, metastasis, non-small-cell lung carcinoma, surgery
Analysis
Brain Neoplasms - secondary
Brain Neoplasms - surgery
Breast cancer
Cancer therapies
Carcinoma, Non-Small-Cell Lung - pathology
Carcinoma, Non-Small-Cell Lung - therapy
Care and treatment
Development and progression
Family medical history
Female
Humans
Lung cancer
Lung cancer, Non-small cell
Lung Neoplasms - pathology
Lung Neoplasms - therapy
Medical imaging
Metastasis
Middle Aged
Patient outcomes
Radiosurgery
Tomography
Treatment Outcome
title Adrenalectomy for isolated adrenal metastasis after Gamma Knife Surgery for an intracerebral metastasis of non-small-cell lung carcinoma
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