Cell proliferation and total granule cell number in dentate gyrus of transgenic Tg2576 mouse

This report provides in vivo evidence of adult neurogenesis and the total granule cell count in the dentate gyrus of the Tg2576 mouse model of Alzheimer's disease. Mice were deeply anaesthetized and perfused with 4 percent buffered paraformaldehyde. Brains were removed and post-fixed in the sam...

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Veröffentlicht in:	Acta neurobiologiae experimentalis 2010-01, Vol.70 (4), p.362-369
Hauptverfasser:	Ihunwo, Amadi O, Schliebs, Reinhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Alzheimer Disease - genetics Alzheimer Disease - pathology Amyloid beta-Protein Precursor - genetics Animals Cell Count Cell Proliferation Dentate Gyrus - pathology Disease Models, Animal Humans Ki-67 Antigen - metabolism Mice Mice, Transgenic Neurons - physiology Presenilin-1 - genetics Species Specificity tau Proteins - genetics
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