NK cell-based approach for screening novel functional immune genes

The human genome project provides extensive opportunities for the discovery of novel functional immune genes. In order to find innate immune genes that might regulate the function of NK cells from a cDNA library, we used an NK cell line, NK-92, as a platform to screen candidate genes. After comparin...

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Veröffentlicht in:	International immunopharmacology 2011-02, Vol.11 (2), p.274-279
Hauptverfasser:	Wu, Longyan, Zhang, Cai, Tian, Zhigang, Zhang, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Cell Line DNA, Complementary - genetics Gene Expression Profiling Genome, Human Humans Immunity, Innate - genetics Innate immunity Killer Cells, Natural - immunology Medical sciences NK cells NK-92 cells Novel functional gene Oligonucleotide Array Sequence Analysis Pharmacology. Drug treatments Reverse Transcriptase Polymerase Chain Reaction
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