Effect of captopril on TNF-α and IL-10 in the livers of bile duct ligated rats

The renin-angiotensin system has an important role in hepatic inflammation and fibrosis. Renin-angiotensin system blockade by angiotensin-converting enzyme (ACE) inhibitors provides some protective effects against hepatic fibrogenesis. Captopril as an ACE inhibitor can decrease inflammatory mediator...

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Veröffentlicht in:	Iranian journal of immunology 2010-12, Vol.7 (4), p.247-251
Hauptverfasser:	Amirshahrokhi, Keyvan, Ghazi-khansari, Mahmoud, Mohammadi-Farani, Ahmad, Karimian, Golnar
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Bile Ducts - surgery Captopril - pharmacology Gene Expression Regulation - drug effects Interleukin-10 - metabolism Ligation Liver - drug effects Liver - metabolism Liver - pathology Liver - surgery Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Liver Cirrhosis - surgery Male Rats Rats, Wistar Tumor Necrosis Factor-alpha - metabolism
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