Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men

Abstract Interleukin-1 (IL-6) is an important mediator of inflammatory response in the respiratory tract during an infection, and the action of IL-6 is mediated by an IL-6 receptor. Several polymorphisms in the IL-6 and IL-6R genes have been associated with different inflammatory disease states. We...

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Veröffentlicht in:	Human immunology 2011, Vol.72 (1), p.63-68
Hauptverfasser:	Rantala, Aino, Lajunen, Taina, Juvonen, Raija, Silvennoinen-Kassinen, Sylvi, Peitso, Ari, Vainio, Olli, Saikku, Pekka, Leinonen, Maija
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Allergy and Immunology Conscript Finland Genetic Association Studies Genetic Predisposition to Disease Genotype Humans IL-6 IL-6 receptor Interleukin-6 - genetics Male Polymorphism Polymorphism, Genetic Polymorphism, Single Nucleotide Receptors, Interleukin-6 - genetics Respiratory tract infection Respiratory Tract Infections - genetics Risk Assessment Young Adult
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