What is a natural killer cell?

Natural killer cells have been arbitrarily defined using a number of different phenotypic and functional criteria. We asked Lorenzo Moretta if we have truly discovered the core identity of this critical player in eliciting immune responses.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nature immunology 2002-01, Vol.3 (1), p.6-8
Hauptverfasser: Moretta, Lorenzo, Moretta, Alessandro, Bottino, Cristina, Mingari, Maria Cristina, Biassoni, Roberto
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 8
container_issue 1
container_start_page 6
container_title Nature immunology
container_volume 3
creator Moretta, Lorenzo
Moretta, Alessandro
Bottino, Cristina
Mingari, Maria Cristina
Biassoni, Roberto
description Natural killer cells have been arbitrarily defined using a number of different phenotypic and functional criteria. We asked Lorenzo Moretta if we have truly discovered the core identity of this critical player in eliciting immune responses.
doi_str_mv 10.1038/ni0102-6
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_864950073</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1013294941</sourcerecordid><originalsourceid>FETCH-LOGICAL-c395t-6316dc363e8b3929cedbf54edb3f3730b5d7c8e39866b1b54a7d512409fda5193</originalsourceid><addsrcrecordid>eNp90U1LwzAcBvAgiptT8BOM4sGXQzXJPy_NacjwDQZeFI8hbVPt7NqZtAe_vZmdGwh6SQL58SR5gtAxwZcEQ3JVl5hgGosdNCScqpgqInY3a5wM0IH3c4wJk4LtowEhkgMoNUTjlzfTRqWPTFSbtnOmit7LqrIuymxVTQ7RXmEqb4_W8wg93948Te_j2ePdw_R6FmegeBsLICLPQIBNUlBUZTZPC87CCAVIwCnPZZZYUIkQKUk5MzLnhDKsitxwomCEzvrcpWs-OutbvSj96gamtk3ndSKY4hhLCPL0XykJMBCUB3jyC86bztXhFZpSKrEKZQR03qPMNd47W-ilKxfGfWqC9apa3VerRaDjdV6XLmy-hesuA7jogQ9b9at12wP_Dvsu3W7Cfj4SvgCPBYfa</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>222709147</pqid></control><display><type>article</type><title>What is a natural killer cell?</title><source>MEDLINE</source><source>Nature</source><source>Springer Nature - Complete Springer Journals</source><creator>Moretta, Lorenzo ; Moretta, Alessandro ; Bottino, Cristina ; Mingari, Maria Cristina ; Biassoni, Roberto</creator><creatorcontrib>Moretta, Lorenzo ; Moretta, Alessandro ; Bottino, Cristina ; Mingari, Maria Cristina ; Biassoni, Roberto</creatorcontrib><description>Natural killer cells have been arbitrarily defined using a number of different phenotypic and functional criteria. We asked Lorenzo Moretta if we have truly discovered the core identity of this critical player in eliciting immune responses.</description><identifier>ISSN: 1529-2908</identifier><identifier>EISSN: 1529-2916</identifier><identifier>DOI: 10.1038/ni0102-6</identifier><identifier>PMID: 11753399</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>Animals ; Biomedical and Life Sciences ; Biomedicine ; Bone Marrow Transplantation ; commentary ; Cytotoxicity, Immunologic ; Evolution, Molecular ; Forecasting ; Histocompatibility Antigens Class I - immunology ; Humans ; Immunologic Surveillance ; Immunology ; Immunotherapy, Adoptive ; Infectious Diseases ; Killer Cells, Natural - classification ; Killer Cells, Natural - cytology ; Killer Cells, Natural - immunology ; Killer Cells, Natural - transplantation ; Lymphocyte Activation - physiology ; Neoplasms - immunology ; Pan troglodytes - immunology ; Receptors, Immunologic - genetics ; Receptors, Immunologic - immunology ; Receptors, KIR ; Rodentia - immunology ; Virus Diseases - immunology</subject><ispartof>Nature immunology, 2002-01, Vol.3 (1), p.6-8</ispartof><rights>Springer Nature America, Inc. 2002</rights><rights>Copyright Nature Publishing Group Jan 2002</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c395t-6316dc363e8b3929cedbf54edb3f3730b5d7c8e39866b1b54a7d512409fda5193</citedby><cites>FETCH-LOGICAL-c395t-6316dc363e8b3929cedbf54edb3f3730b5d7c8e39866b1b54a7d512409fda5193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/ni0102-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/ni0102-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27911,27912,41475,42544,51306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11753399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Moretta, Lorenzo</creatorcontrib><creatorcontrib>Moretta, Alessandro</creatorcontrib><creatorcontrib>Bottino, Cristina</creatorcontrib><creatorcontrib>Mingari, Maria Cristina</creatorcontrib><creatorcontrib>Biassoni, Roberto</creatorcontrib><title>What is a natural killer cell?</title><title>Nature immunology</title><addtitle>Nat Immunol</addtitle><addtitle>Nat Immunol</addtitle><description>Natural killer cells have been arbitrarily defined using a number of different phenotypic and functional criteria. We asked Lorenzo Moretta if we have truly discovered the core identity of this critical player in eliciting immune responses.</description><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Bone Marrow Transplantation</subject><subject>commentary</subject><subject>Cytotoxicity, Immunologic</subject><subject>Evolution, Molecular</subject><subject>Forecasting</subject><subject>Histocompatibility Antigens Class I - immunology</subject><subject>Humans</subject><subject>Immunologic Surveillance</subject><subject>Immunology</subject><subject>Immunotherapy, Adoptive</subject><subject>Infectious Diseases</subject><subject>Killer Cells, Natural - classification</subject><subject>Killer Cells, Natural - cytology</subject><subject>Killer Cells, Natural - immunology</subject><subject>Killer Cells, Natural - transplantation</subject><subject>Lymphocyte Activation - physiology</subject><subject>Neoplasms - immunology</subject><subject>Pan troglodytes - immunology</subject><subject>Receptors, Immunologic - genetics</subject><subject>Receptors, Immunologic - immunology</subject><subject>Receptors, KIR</subject><subject>Rodentia - immunology</subject><subject>Virus Diseases - immunology</subject><issn>1529-2908</issn><issn>1529-2916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp90U1LwzAcBvAgiptT8BOM4sGXQzXJPy_NacjwDQZeFI8hbVPt7NqZtAe_vZmdGwh6SQL58SR5gtAxwZcEQ3JVl5hgGosdNCScqpgqInY3a5wM0IH3c4wJk4LtowEhkgMoNUTjlzfTRqWPTFSbtnOmit7LqrIuymxVTQ7RXmEqb4_W8wg93948Te_j2ePdw_R6FmegeBsLICLPQIBNUlBUZTZPC87CCAVIwCnPZZZYUIkQKUk5MzLnhDKsitxwomCEzvrcpWs-OutbvSj96gamtk3ndSKY4hhLCPL0XykJMBCUB3jyC86bztXhFZpSKrEKZQR03qPMNd47W-ilKxfGfWqC9apa3VerRaDjdV6XLmy-hesuA7jogQ9b9at12wP_Dvsu3W7Cfj4SvgCPBYfa</recordid><startdate>200201</startdate><enddate>200201</enddate><creator>Moretta, Lorenzo</creator><creator>Moretta, Alessandro</creator><creator>Bottino, Cristina</creator><creator>Mingari, Maria Cristina</creator><creator>Biassoni, Roberto</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>200201</creationdate><title>What is a natural killer cell?</title><author>Moretta, Lorenzo ; Moretta, Alessandro ; Bottino, Cristina ; Mingari, Maria Cristina ; Biassoni, Roberto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c395t-6316dc363e8b3929cedbf54edb3f3730b5d7c8e39866b1b54a7d512409fda5193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Bone Marrow Transplantation</topic><topic>commentary</topic><topic>Cytotoxicity, Immunologic</topic><topic>Evolution, Molecular</topic><topic>Forecasting</topic><topic>Histocompatibility Antigens Class I - immunology</topic><topic>Humans</topic><topic>Immunologic Surveillance</topic><topic>Immunology</topic><topic>Immunotherapy, Adoptive</topic><topic>Infectious Diseases</topic><topic>Killer Cells, Natural - classification</topic><topic>Killer Cells, Natural - cytology</topic><topic>Killer Cells, Natural - immunology</topic><topic>Killer Cells, Natural - transplantation</topic><topic>Lymphocyte Activation - physiology</topic><topic>Neoplasms - immunology</topic><topic>Pan troglodytes - immunology</topic><topic>Receptors, Immunologic - genetics</topic><topic>Receptors, Immunologic - immunology</topic><topic>Receptors, KIR</topic><topic>Rodentia - immunology</topic><topic>Virus Diseases - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Moretta, Lorenzo</creatorcontrib><creatorcontrib>Moretta, Alessandro</creatorcontrib><creatorcontrib>Bottino, Cristina</creatorcontrib><creatorcontrib>Mingari, Maria Cristina</creatorcontrib><creatorcontrib>Biassoni, Roberto</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Moretta, Lorenzo</au><au>Moretta, Alessandro</au><au>Bottino, Cristina</au><au>Mingari, Maria Cristina</au><au>Biassoni, Roberto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What is a natural killer cell?</atitle><jtitle>Nature immunology</jtitle><stitle>Nat Immunol</stitle><addtitle>Nat Immunol</addtitle><date>2002-01</date><risdate>2002</risdate><volume>3</volume><issue>1</issue><spage>6</spage><epage>8</epage><pages>6-8</pages><issn>1529-2908</issn><eissn>1529-2916</eissn><abstract>Natural killer cells have been arbitrarily defined using a number of different phenotypic and functional criteria. We asked Lorenzo Moretta if we have truly discovered the core identity of this critical player in eliciting immune responses.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>11753399</pmid><doi>10.1038/ni0102-6</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1529-2908
ispartof Nature immunology, 2002-01, Vol.3 (1), p.6-8
issn 1529-2908
1529-2916
language eng
recordid cdi_proquest_miscellaneous_864950073
source MEDLINE; Nature; Springer Nature - Complete Springer Journals
subjects Animals
Biomedical and Life Sciences
Biomedicine
Bone Marrow Transplantation
commentary
Cytotoxicity, Immunologic
Evolution, Molecular
Forecasting
Histocompatibility Antigens Class I - immunology
Humans
Immunologic Surveillance
Immunology
Immunotherapy, Adoptive
Infectious Diseases
Killer Cells, Natural - classification
Killer Cells, Natural - cytology
Killer Cells, Natural - immunology
Killer Cells, Natural - transplantation
Lymphocyte Activation - physiology
Neoplasms - immunology
Pan troglodytes - immunology
Receptors, Immunologic - genetics
Receptors, Immunologic - immunology
Receptors, KIR
Rodentia - immunology
Virus Diseases - immunology
title What is a natural killer cell?
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T21%3A15%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=What%20is%20a%20natural%20killer%20cell?&rft.jtitle=Nature%20immunology&rft.au=Moretta,%20Lorenzo&rft.date=2002-01&rft.volume=3&rft.issue=1&rft.spage=6&rft.epage=8&rft.pages=6-8&rft.issn=1529-2908&rft.eissn=1529-2916&rft_id=info:doi/10.1038/ni0102-6&rft_dat=%3Cproquest_cross%3E1013294941%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=222709147&rft_id=info:pmid/11753399&rfr_iscdi=true