A Mathematical Model for Timing the Release from Sequestration and the Resultant Brownian Migration of SeqA Clusters in E. coli

DNA replication in Escherichia coli is initiated by DnaA binding to oriC , the replication origin. During the process of assembly of the replication factory, the DnaA is released back into the cytoplasm, where it is competent to reinitiate replication. Premature reinitiation is prevented by binding...

Ausführliche Beschreibung