Effect of combined lignan phytoestrogen and melatonin treatment on secretion of steroid hormones by adrenal carcinoma cells

Objective—To investigate the in vitro effect of the combination of lignan enterolactone (ENL) or lignan enterodiol (END) with melatonin on steroid hormone secretion and cellular aromatase content in human adrenal carcinoma cells. Sample—Human adrenocortical carcinoma cells. Procedures—Melatonin plus...

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Veröffentlicht in:	American journal of veterinary research 2011-05, Vol.72 (5), p.675-680
Hauptverfasser:	Fecteau, Kellie A, Eiler, Hugo, Oliver, Jack W
Format:	Artikel
Sprache:	eng
Schlagworte:	17-hydroxyprogesterone 4-Butyrolactone - analogs & derivatives 4-Butyrolactone - pharmacology adrenal glands Adrenal Glands - drug effects Adrenal Glands - metabolism aldosterone androstenedione Animals aromatase Aromatase - metabolism carcinoma cell culture Cell Line cortisol culture media Cyclic AMP - metabolism Dogs estradiol hormone secretion Humans hyperadrenocorticism lignans Lignans - pharmacology melatonin Melatonin - pharmacology neoplasm cells Phytoestrogens - pharmacology radioimmunoassays steroid hormones Steroids - analysis Steroids - biosynthesis Western blotting
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