Control of Ca[super]2+ Release by Action Potential Configuration in Normal and Failing Murine Cardiomyocytes

Cardiomyocytes from failing hearts exhibit spatially nonuniform or dyssynchronous sarcoplasmic reticulum (SR) Ca[super]2+ release. We investigated the contribution of action potential (AP) prolongation in mice with congestive heart failure (CHF) after myocardial infarction. AP recordings from CHF an...

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Veröffentlicht in:	Biophysical journal 2010-09, Vol.99 (5), p.1377-1386
Hauptverfasser:	Louch, William E, Hake, Johan, Joelle, Guro Five, Moerk, Halvor K, Sjaastad, Ivar, Lines, Glenn T, Sejersted, Ole M
Format:	Artikel
Sprache:	eng
Schlagworte:	Failure Heart Mathematical models Mice Nonuniform Prolongation Receptors Trains
Online-Zugang:	Volltext
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