European consumer exposure to cosmetic products, a framework for conducting population exposure assessments Part 2

Access to reliable exposure data is essential for the evaluation of the toxicological safety of ingredients in cosmetic products. This study complements the data set obtained previously (Part 1) and published in 2007 by the European cosmetic industry acting within COLIPA. It provides, in distributio...

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Veröffentlicht in:Food and chemical toxicology 2011-02, Vol.49 (2), p.408-422
Hauptverfasser: Hall, B., Steiling, W., Safford, B., Coroama, M., Tozer, S., Firmani, C., McNamara, C., Gibney, M.
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container_end_page 422
container_issue 2
container_start_page 408
container_title Food and chemical toxicology
container_volume 49
creator Hall, B.
Steiling, W.
Safford, B.
Coroama, M.
Tozer, S.
Firmani, C.
McNamara, C.
Gibney, M.
description Access to reliable exposure data is essential for the evaluation of the toxicological safety of ingredients in cosmetic products. This study complements the data set obtained previously (Part 1) and published in 2007 by the European cosmetic industry acting within COLIPA. It provides, in distribution form, exposure data on daily quantities of five cosmetic product types: hair styling, hand cream, liquid foundation, mouthwash and shower gel. In total 80,000 households and 14,413 individual consumers in five European countries provided information using their own products. The raw data were analysed using Monte Carlo simulation and a European Statistical Population Model of exposure was constructed. A significant finding was an inverse correlation between the frequency of product use and the quantity used per application recorded for mouthwash and shower gel. The combined results of Part 1 (7 product types) and Part 2 (5 products) reported here, bring up to date and largely confirm the current exposure parameters concerning some 95% of the estimated daily exposure to cosmetics use in the EU. The design of this study, with its relation to demographic and individual diversity, could serve as a model for studies of populations’ exposure to other consumer products.
doi_str_mv 10.1016/j.fct.2010.11.016
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source MEDLINE; Elsevier ScienceDirect Journals Complete
subjects at-risk population
Biological and medical sciences
Consumer Product Safety
Cosmetics
Cosmetics - administration & dosage
Cosmetics - adverse effects
cream
data collection
Domestic and cosmetic products toxicology
Europe
European Union
experimental design
Exposure
exposure models
gels
households
Humans
industry
ingredients
Medical sciences
Monte Carlo
Monte Carlo method
Population Surveillance
Probabilistic analysis
Statistical population modelling
Toxicology
title European consumer exposure to cosmetic products, a framework for conducting population exposure assessments Part 2
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