A novel VIM‐type metallo‐beta‐lactamase (VIM‐14) in a Pseudomonas aeruginosa clinical isolate from a neonatal intensive care unit

A Pseudomonas aeruginosa highly resistant to carbapenems was isolated in a neonatal intensive care unit in Palermo, Italy. The strain was found to carry a novel VIM‐type enzyme, classified as VIM‐14. The novel enzyme differs from VIM‐4 in a G31S mutation. VIM‐14 was harboured in a class 1 integron w...

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Veröffentlicht in:	Clinical microbiology and infection 2011-05, Vol.17 (5), p.722-724
Hauptverfasser:	Mazzariol, A., Mammina, C., Koncan, R., Di Gaetano, V., Di Carlo, P., Cipolla, D., Corsello, G., Cornaglia, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial agents Antibiotic resistance Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteriology Base Sequence beta-Lactamases - genetics beta-Lactamases - metabolism Biological and medical sciences carbapenems Carbapenems - pharmacology DNA, Bacterial - genetics Drug Resistance, Multiple, Bacterial - genetics Enzymes Humans Infant, Newborn Infectious diseases Integrons - drug effects Intensive care Intensive Care Units, Neonatal Medical sciences metallo‐β‐lactamase Microbial Sensitivity Tests Molecular Sequence Data Pharmacology. Drug treatments Pseudomonas aeruginosa Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - enzymology Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - isolation & purification Sequence Analysis, DNA VIM‐14
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