Sequential coupling/desilylation-coupling/cyclization in a single pot under Pd/C-Cu catalysis: synthesis of 2-(hetero)aryl indoles

A new one-pot synthesis of 2-(hetero)aryl indoles via sequential C-C coupling followed by C-Si bond cleavage and a subsequent tandem C-C/C-N bond forming reaction is described. A variety of functionalized indole derivatives were prepared by conducting this four step reaction under Pd/C-Cu catalysis....

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Veröffentlicht in:Organic & biomolecular chemistry 2011-05, Vol.9 (10), p.3808-3816
Hauptverfasser: Rao, R Mohan, Reddy, Upendar C H, Alinakhi, Mulakayala, Naveen, Alvala, Mallika, Arunasree, M K, Poondra, Rajamohan R, Iqbal, Javed, Pal, Manojit
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Sprache:eng
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