EGFR in melanoma: clinical significance and potential therapeutic target

Background: The role of epidermal growth factor receptor (EGFR) has been established in a range of neoplasms. In melanoma, data on EGFR protein expression are conflicting. Fluorescence in situ hybridization (FISH) analysis for EGFR gene expression in melanoma showed EGFR gene amplification to be lin...

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Veröffentlicht in:	Journal of cutaneous pathology 2011-06, Vol.38 (6), p.492-502
Hauptverfasser:	Boone, Barbara, Jacobs, Koen, Ferdinande, Liesbeth, Taildeman, Jasmien, Lambert, Jo, Peeters, Marc, Bracke, Marc, Pauwels, Patrick, Brochez, Lieve
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Blotting, Western cancer research Dermatology dermatopathology Female Gene Dosage Gene Expression Gene Expression Profiling Humans Immunohistochemistry In Situ Hybridization, Fluorescence Male malignant melanoma Medical sciences Melanoma - genetics Melanoma - pathology Middle Aged Prognosis Receptor, Epidermal Growth Factor - biosynthesis Receptor, Epidermal Growth Factor - genetics Skin Neoplasms - genetics Skin Neoplasms - pathology Tumors of the skin and soft tissue. Premalignant lesions
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