Minimax optimization for handling range and setup uncertainties in proton therapy
Purpose: Intensity modulated proton therapy (IMPT) is sensitive to errors, mainly due to high stopping power dependency and steep beam dose gradients. Conventional margins are often insufficient to ensure robustness of treatment plans. In this article, a method is developed that takes the uncertaint...
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Veröffentlicht in: | Medical physics (Lancaster) 2011-03, Vol.38 (3), p.1672-1684 |
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Format: | Artikel |
Sprache: | eng |
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