Rab7 is a critical mediator in vesicular transport of tyrosinase-related protein 1 in melanocytes

How melanosomal proteins such as enzymic proteins (tyrosinase and tyrosinase‐related proteins, Tyrps) and structural protein (gp100) are transported from Golgi to melanosomal compartments is not yet fully understood. A number of small GTPases have been found to be associated with melanosomes and we...

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Veröffentlicht in:	Journal of dermatology 2011-05, Vol.38 (5), p.432-441
Hauptverfasser:	HIDA, Tokimasa, SOHMA, Hitoshi, KOKAI, Yasuo, KAWAKAMI, Akinori, HIROSAKI, Kuninori, OKURA, Masae, TOSA, Noriko, YAMASHITA, Toshiharu, JIMBOW, Kowichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Golgi Apparatus - metabolism gp100 gp100 Melanoma Antigen - metabolism Melanins - biosynthesis Melanocytes - metabolism melanogenesis melanosome Melanosomes - metabolism Mice Monophenol Monooxygenase - metabolism Oxidoreductases - metabolism Protein Transport rab GTP-Binding Proteins - genetics rab GTP-Binding Proteins - physiology Transfection tyrosinase tyrosinase-related protein Tyrp1
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