Assessment of Canine Vocal Fold Function after Injection of a New Biomaterial Designed to Treat Phonatory Mucosal Scarring

Objectives: Most cases of irresolvable hoarseness are due to deficiencies in the pliability and volume of the superficial lamina propria of the phonatory mucosa. By using a US Food and Drug Administration–approved polymer, polyethylene glycol (PEG), we created a novel hydrogel (PEG30) and investigat...

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Veröffentlicht in:	Annals of otology, rhinology & laryngology rhinology & laryngology, 2011-03, Vol.120 (3), p.175-184
Hauptverfasser:	Karajanagi, Sandeep S., Lopez-Guerra, Gerardo, Park, Hyoungshin, Kobler, James B., Galindo, Marilyn, Aanestad, Jon, Mehta, Daryush D., Kumai, Yoshihiko, Giordano, Nicholas, d'Almeida, Anthony, Heaton, James T., Langer, Robert, Herrera, Victoria L. M., Faquin, William, Hillman, Robert E., Zeitels, Steven M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Dogs Elasticity Fibrosis Hydrogels - pharmacology Injections Laryngeal Mucosa - drug effects Laryngoscopy Larynx - pathology Macrophages - pathology Magnetic Resonance Imaging Male Medical sciences Models, Animal Non tumoral diseases Otorhinolaryngology. Stomatology Phagocytosis Phonation Polyethylene Glycols - pharmacology Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology Viscosity Vocal Cords - drug effects
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