Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature
Objectives: The aim of this prospective study was to evaluate the outcome of treatment of a group of 17 patients with central giant cell granuloma (CGCG) who were treated in our clinic. Methods: A group of 17 patients with CGCG were treated in the Clinic of Oral and Maxillofacial Surgery of the “G....
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| Veröffentlicht in: | Annals of otology, rhinology & laryngology rhinology & laryngology, 2011-03, Vol.120 (3), p.167-174 |
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| container_title | Annals of otology, rhinology & laryngology |
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| creator | Triantafillidou, Katherine Venetis, Grigoris Karakinaris, George Iordanidis, Fotis |
| description | Objectives:
The aim of this prospective study was to evaluate the outcome of treatment of a group of 17 patients with central giant cell granuloma (CGCG) who were treated in our clinic.
Methods:
A group of 17 patients with CGCG were treated in the Clinic of Oral and Maxillofacial Surgery of the “G. Papanikolaou” hospital in Thessaloniki. The age range was from 7 to 60 years. Eight patients were male and 9 patients were female. Because most of our patients (11) were less than 30 years old, the aim of the treatment was to eradicate the lesions without functional problems. All of the patients were treated by excision via curettage without a continuity defect and peripheral osteotomy. For 2 patients, the treatment was continued (after the first recurrence) with salmon calcitonin.
Results:
The follow-ups ranged from 1 to 15 years. All of the patients were free of the disease, without features of recurrence and without functional or aesthetic problems.
Conclusions:
Surgery has usually been considered to be the best method of treatment for CGCG. Most authors have proposed conservative surgical procedures (excision via curettage), especially for young patients. For aggressive lesions, supplementary treatment with calcitonin would provide good results. |
| doi_str_mv | 10.1177/000348941112000305 |
| format | Article |
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The aim of this prospective study was to evaluate the outcome of treatment of a group of 17 patients with central giant cell granuloma (CGCG) who were treated in our clinic.
Methods:
A group of 17 patients with CGCG were treated in the Clinic of Oral and Maxillofacial Surgery of the “G. Papanikolaou” hospital in Thessaloniki. The age range was from 7 to 60 years. Eight patients were male and 9 patients were female. Because most of our patients (11) were less than 30 years old, the aim of the treatment was to eradicate the lesions without functional problems. All of the patients were treated by excision via curettage without a continuity defect and peripheral osteotomy. For 2 patients, the treatment was continued (after the first recurrence) with salmon calcitonin.
Results:
The follow-ups ranged from 1 to 15 years. All of the patients were free of the disease, without features of recurrence and without functional or aesthetic problems.
Conclusions:
Surgery has usually been considered to be the best method of treatment for CGCG. Most authors have proposed conservative surgical procedures (excision via curettage), especially for young patients. For aggressive lesions, supplementary treatment with calcitonin would provide good results.</description><identifier>ISSN: 0003-4894</identifier><identifier>EISSN: 1943-572X</identifier><identifier>DOI: 10.1177/000348941112000305</identifier><identifier>PMID: 21510142</identifier><identifier>CODEN: AORHA2</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Bone Density Conservation Agents - therapeutic use ; Calcitonin - therapeutic use ; Child ; Curettage ; Dermatology ; Female ; Follow-Up Studies ; Granuloma, Giant Cell - pathology ; Granuloma, Giant Cell - surgery ; Humans ; Jaw Diseases - pathology ; Jaw Diseases - surgery ; Male ; Mandible - surgery ; Maxilla - surgery ; Medical sciences ; Middle Aged ; Osteotomy ; Otorhinolaryngology. Stomatology ; Skin involvement in other diseases. Miscellaneous. General aspects ; Young Adult</subject><ispartof>Annals of otology, rhinology & laryngology, 2011-03, Vol.120 (3), p.167-174</ispartof><rights>2011 SAGE Publications</rights><rights>2015 INIST-CNRS</rights><rights>Copyright Annals Publishing Company Mar 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-2ee8affeb7f7c7cb08a7141457367d7d4b8131d72be74b4b50d666c46e2bb62b3</citedby><cites>FETCH-LOGICAL-c465t-2ee8affeb7f7c7cb08a7141457367d7d4b8131d72be74b4b50d666c46e2bb62b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000348941112000305$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000348941112000305$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24010051$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21510142$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Triantafillidou, Katherine</creatorcontrib><creatorcontrib>Venetis, Grigoris</creatorcontrib><creatorcontrib>Karakinaris, George</creatorcontrib><creatorcontrib>Iordanidis, Fotis</creatorcontrib><title>Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature</title><title>Annals of otology, rhinology & laryngology</title><addtitle>Ann Otol Rhinol Laryngol</addtitle><description>Objectives:
The aim of this prospective study was to evaluate the outcome of treatment of a group of 17 patients with central giant cell granuloma (CGCG) who were treated in our clinic.
Methods:
A group of 17 patients with CGCG were treated in the Clinic of Oral and Maxillofacial Surgery of the “G. Papanikolaou” hospital in Thessaloniki. The age range was from 7 to 60 years. Eight patients were male and 9 patients were female. Because most of our patients (11) were less than 30 years old, the aim of the treatment was to eradicate the lesions without functional problems. All of the patients were treated by excision via curettage without a continuity defect and peripheral osteotomy. For 2 patients, the treatment was continued (after the first recurrence) with salmon calcitonin.
Results:
The follow-ups ranged from 1 to 15 years. All of the patients were free of the disease, without features of recurrence and without functional or aesthetic problems.
Conclusions:
Surgery has usually been considered to be the best method of treatment for CGCG. Most authors have proposed conservative surgical procedures (excision via curettage), especially for young patients. For aggressive lesions, supplementary treatment with calcitonin would provide good results.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Bone Density Conservation Agents - therapeutic use</subject><subject>Calcitonin - therapeutic use</subject><subject>Child</subject><subject>Curettage</subject><subject>Dermatology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Granuloma, Giant Cell - pathology</subject><subject>Granuloma, Giant Cell - surgery</subject><subject>Humans</subject><subject>Jaw Diseases - pathology</subject><subject>Jaw Diseases - surgery</subject><subject>Male</subject><subject>Mandible - surgery</subject><subject>Maxilla - surgery</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Osteotomy</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Skin involvement in other diseases. Miscellaneous. General aspects</subject><subject>Young Adult</subject><issn>0003-4894</issn><issn>1943-572X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kdtKxDAQhoMouh5ewAsJgnhVN5Pm0PVuKR5ZEDyAdyVpp1rptpq0Lr69KbsqKHiVSeb7JzP_ELIP7ARA6zFjLBbJRAAAH2Im18gIJiKOpOaP62Q0PEYDsUW2vX8JVyEZ3yRbHCQwEHxEMMWmc6amF5VpOppiHUJnmr5u54a2Je2ekV6bhT-lU5rWVVPlAb7r-uJjyIKmqfHoqWkKaugtvle4-JLNqg6d6XqHu2SjNLXHvdW5Qx7Oz-7Ty2h2c3GVTmdRLpTsIo6YmLJEq0ud69yyxGgQIKSOlS50IWwCMRSaW9TCCitZoZQKWuTWKm7jHXK8rPvq2rcefZfNK5-HmUyDbe-zRMUi5krpQB7-Il_a3jWhuSyRSkk9kXGA-BLKXeu9wzJ7ddXcuI8MWDasIPu7giA6WFXu7RyLb8mX5wE4WgHGBzPL4HZe-R9OMGBMQuDGS86bJ_xp75-vPwF0tJg-</recordid><startdate>20110301</startdate><enddate>20110301</enddate><creator>Triantafillidou, Katherine</creator><creator>Venetis, Grigoris</creator><creator>Karakinaris, George</creator><creator>Iordanidis, Fotis</creator><general>SAGE Publications</general><general>Annals Publishing Compagny</general><general>SAGE PUBLICATIONS, INC</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>20110301</creationdate><title>Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature</title><author>Triantafillidou, Katherine ; Venetis, Grigoris ; Karakinaris, George ; Iordanidis, Fotis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-2ee8affeb7f7c7cb08a7141457367d7d4b8131d72be74b4b50d666c46e2bb62b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Bone Density Conservation Agents - therapeutic use</topic><topic>Calcitonin - therapeutic use</topic><topic>Child</topic><topic>Curettage</topic><topic>Dermatology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Granuloma, Giant Cell - pathology</topic><topic>Granuloma, Giant Cell - surgery</topic><topic>Humans</topic><topic>Jaw Diseases - pathology</topic><topic>Jaw Diseases - surgery</topic><topic>Male</topic><topic>Mandible - surgery</topic><topic>Maxilla - surgery</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Osteotomy</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Skin involvement in other diseases. Miscellaneous. General aspects</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Triantafillidou, Katherine</creatorcontrib><creatorcontrib>Venetis, Grigoris</creatorcontrib><creatorcontrib>Karakinaris, George</creatorcontrib><creatorcontrib>Iordanidis, Fotis</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Annals of otology, rhinology & laryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Triantafillidou, Katherine</au><au>Venetis, Grigoris</au><au>Karakinaris, George</au><au>Iordanidis, Fotis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature</atitle><jtitle>Annals of otology, rhinology & laryngology</jtitle><addtitle>Ann Otol Rhinol Laryngol</addtitle><date>2011-03-01</date><risdate>2011</risdate><volume>120</volume><issue>3</issue><spage>167</spage><epage>174</epage><pages>167-174</pages><issn>0003-4894</issn><eissn>1943-572X</eissn><coden>AORHA2</coden><abstract>Objectives:
The aim of this prospective study was to evaluate the outcome of treatment of a group of 17 patients with central giant cell granuloma (CGCG) who were treated in our clinic.
Methods:
A group of 17 patients with CGCG were treated in the Clinic of Oral and Maxillofacial Surgery of the “G. Papanikolaou” hospital in Thessaloniki. The age range was from 7 to 60 years. Eight patients were male and 9 patients were female. Because most of our patients (11) were less than 30 years old, the aim of the treatment was to eradicate the lesions without functional problems. All of the patients were treated by excision via curettage without a continuity defect and peripheral osteotomy. For 2 patients, the treatment was continued (after the first recurrence) with salmon calcitonin.
Results:
The follow-ups ranged from 1 to 15 years. All of the patients were free of the disease, without features of recurrence and without functional or aesthetic problems.
Conclusions:
Surgery has usually been considered to be the best method of treatment for CGCG. Most authors have proposed conservative surgical procedures (excision via curettage), especially for young patients. For aggressive lesions, supplementary treatment with calcitonin would provide good results.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>21510142</pmid><doi>10.1177/000348941112000305</doi><tpages>8</tpages></addata></record> |
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| ispartof | Annals of otology, rhinology & laryngology, 2011-03, Vol.120 (3), p.167-174 |
| issn | 0003-4894 1943-572X |
| language | eng |
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| subjects | Adolescent Adult Biological and medical sciences Bone Density Conservation Agents - therapeutic use Calcitonin - therapeutic use Child Curettage Dermatology Female Follow-Up Studies Granuloma, Giant Cell - pathology Granuloma, Giant Cell - surgery Humans Jaw Diseases - pathology Jaw Diseases - surgery Male Mandible - surgery Maxilla - surgery Medical sciences Middle Aged Osteotomy Otorhinolaryngology. Stomatology Skin involvement in other diseases. Miscellaneous. General aspects Young Adult |
| title | Central Giant Cell Granuloma of the Jaws: A Clinical Study of 17 Cases and a Review of the Literature |
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