Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase ( GOAT ) is associated with anorexia nervosa

Abstract The gastrointestinal peptide hormone ghrelin promotes food intake and increases body weight and adiposity through activation of the growth hormone secretagogue receptor (GHSR1a). To promote its biological action ghrelin is acylated at its serine 3 residue by the recently discovered ghrelin...

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Veröffentlicht in:	Journal of psychiatric research 2011-05, Vol.45 (5), p.706-711
Hauptverfasser:	Müller, Timo D, Tschöp, Matthias H, Jarick, Ivonne, Ehrlich, Stefan, Scherag, Susann, Herpertz-Dahlmann, Beate, Zipfel, Stefan, Herzog, Wolfgang, de Zwaan, Martina, Burghardt, Roland, Fleischhaker, Christian, Klampfl, Karin, Wewetzer, Christoph, Herpertz, Stephan, Zeeck, Almut, Tagay, Sefik, Burgmer, Markus, Pfluger, Paul T, Scherag, André, Hebebrand, Johannes, Hinney, Anke
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyltransferases - genetics Adult and adolescent clinical studies Aetiology Anorexia nervosa Anorexia Nervosa - genetics Association study Biological and medical sciences Body Mass Index Eating behavior disorders Female Gene Frequency Genetic Predisposition to Disease Genetic variation Genome-Wide Association Study Genotype Ghrelin GOAT Hormones Humans Male Medical sciences Odds Ratio Plasma levels Polymorphism, Single Nucleotide - genetics Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry
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