Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program

Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated wi...

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Veröffentlicht in:Annals of emergency medicine 2011-05, Vol.57 (5), p.510-516
Hauptverfasser: Torres Macho, Juan, MD, Peña Lillo, Gabriela, MD, Pérez Martínez, David, MD, González Mansilla, Ana, MD, Gámez Díez, Sergio, MD, Mateo Alvarez, Salvador, MD, García de Casasola, Gonzalo, MD
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container_end_page 516
container_issue 5
container_start_page 510
container_title Annals of emergency medicine
container_volume 57
creator Torres Macho, Juan, MD
Peña Lillo, Gabriela, MD
Pérez Martínez, David, MD
González Mansilla, Ana, MD
Gámez Díez, Sergio, MD
Mateo Alvarez, Salvador, MD
García de Casasola, Gonzalo, MD
description Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.
doi_str_mv 10.1016/j.annemergmed.2010.09.009
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The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.</description><identifier>ISSN: 0196-0644</identifier><identifier>EISSN: 1097-6760</identifier><identifier>DOI: 10.1016/j.annemergmed.2010.09.009</identifier><identifier>PMID: 21131102</identifier><identifier>CODEN: AEMED3</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Carotid Stenosis - diagnosis ; Carotid Stenosis - therapy ; Emergency ; Emergency and intensive care: techniques, logistics ; Emergency Service, Hospital - statistics &amp; numerical data ; Female ; Humans ; Incidence ; Intensive care medicine ; Intensive care unit. Emergency transport systems. Emergency, hospital ward ; Ischemic Attack, Transient - diagnosis ; Ischemic Attack, Transient - therapy ; Kaplan-Meier Estimate ; Male ; Medical sciences ; Prognosis ; Prospective Studies ; Recurrence ; Risk Factors ; Severity of Illness Index ; Stroke - diagnosis ; Stroke - therapy ; Time Factors ; Treatment Outcome</subject><ispartof>Annals of emergency medicine, 2011-05, Vol.57 (5), p.510-516</ispartof><rights>American College of Emergency Physicians</rights><rights>2010 American College of Emergency Physicians</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 American College of Emergency Physicians. 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The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. 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Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Carotid Stenosis - diagnosis</topic><topic>Carotid Stenosis - therapy</topic><topic>Emergency</topic><topic>Emergency and intensive care: techniques, logistics</topic><topic>Emergency Service, Hospital - statistics &amp; numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Intensive care medicine</topic><topic>Intensive care unit. Emergency transport systems. 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The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>21131102</pmid><doi>10.1016/j.annemergmed.2010.09.009</doi><tpages>7</tpages></addata></record>
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subjects Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Carotid Stenosis - diagnosis
Carotid Stenosis - therapy
Emergency
Emergency and intensive care: techniques, logistics
Emergency Service, Hospital - statistics & numerical data
Female
Humans
Incidence
Intensive care medicine
Intensive care unit. Emergency transport systems. Emergency, hospital ward
Ischemic Attack, Transient - diagnosis
Ischemic Attack, Transient - therapy
Kaplan-Meier Estimate
Male
Medical sciences
Prognosis
Prospective Studies
Recurrence
Risk Factors
Severity of Illness Index
Stroke - diagnosis
Stroke - therapy
Time Factors
Treatment Outcome
title Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program
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