Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program
Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated wi...
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Veröffentlicht in: | Annals of emergency medicine 2011-05, Vol.57 (5), p.510-516 |
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creator | Torres Macho, Juan, MD Peña Lillo, Gabriela, MD Pérez Martínez, David, MD González Mansilla, Ana, MD Gámez Díez, Sergio, MD Mateo Alvarez, Salvador, MD García de Casasola, Gonzalo, MD |
description | Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk. |
doi_str_mv | 10.1016/j.annemergmed.2010.09.009 |
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The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.</description><identifier>ISSN: 0196-0644</identifier><identifier>EISSN: 1097-6760</identifier><identifier>DOI: 10.1016/j.annemergmed.2010.09.009</identifier><identifier>PMID: 21131102</identifier><identifier>CODEN: AEMED3</identifier><language>eng</language><publisher>New York, NY: Mosby, Inc</publisher><subject>Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Carotid Stenosis - diagnosis ; Carotid Stenosis - therapy ; Emergency ; Emergency and intensive care: techniques, logistics ; Emergency Service, Hospital - statistics & numerical data ; Female ; Humans ; Incidence ; Intensive care medicine ; Intensive care unit. Emergency transport systems. Emergency, hospital ward ; Ischemic Attack, Transient - diagnosis ; Ischemic Attack, Transient - therapy ; Kaplan-Meier Estimate ; Male ; Medical sciences ; Prognosis ; Prospective Studies ; Recurrence ; Risk Factors ; Severity of Illness Index ; Stroke - diagnosis ; Stroke - therapy ; Time Factors ; Treatment Outcome</subject><ispartof>Annals of emergency medicine, 2011-05, Vol.57 (5), p.510-516</ispartof><rights>American College of Emergency Physicians</rights><rights>2010 American College of Emergency Physicians</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c461t-6a0d55d9f35a420a01634525bd8078c25b587bc6ceea6e27320fab0c9347bba63</citedby><cites>FETCH-LOGICAL-c461t-6a0d55d9f35a420a01634525bd8078c25b587bc6ceea6e27320fab0c9347bba63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.annemergmed.2010.09.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27929,27930,46000</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24200003$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21131102$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Torres Macho, Juan, MD</creatorcontrib><creatorcontrib>Peña Lillo, Gabriela, MD</creatorcontrib><creatorcontrib>Pérez Martínez, David, MD</creatorcontrib><creatorcontrib>González Mansilla, Ana, MD</creatorcontrib><creatorcontrib>Gámez Díez, Sergio, MD</creatorcontrib><creatorcontrib>Mateo Alvarez, Salvador, MD</creatorcontrib><creatorcontrib>García de Casasola, Gonzalo, MD</creatorcontrib><title>Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program</title><title>Annals of emergency medicine</title><addtitle>Ann Emerg Med</addtitle><description>Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.</description><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Carotid Stenosis - diagnosis</subject><subject>Carotid Stenosis - therapy</subject><subject>Emergency</subject><subject>Emergency and intensive care: techniques, logistics</subject><subject>Emergency Service, Hospital - statistics & numerical data</subject><subject>Female</subject><subject>Humans</subject><subject>Incidence</subject><subject>Intensive care medicine</subject><subject>Intensive care unit. Emergency transport systems. Emergency, hospital ward</subject><subject>Ischemic Attack, Transient - diagnosis</subject><subject>Ischemic Attack, Transient - therapy</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Recurrence</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Stroke - diagnosis</subject><subject>Stroke - therapy</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0196-0644</issn><issn>1097-6760</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNks9uEzEQxi0EoqHwCsgcEKcN4_2b5YAUhQKVWhXRcra83tnEya6d2l6kPAWvzGyTCsQJX2yNf_PN-Bsz9kbAXIAo32_nyloc0K8HbOcpUBzqOUD9hM0E1FVSViU8ZTMQdZlAmedn7EUIWyAiT8VzdpYKkQkB6Yz9uhmjdgMG7jq-jBv0Lm68GxoXjeZ3Xtlg0EZ-GfQGBwotY1R6x5Vt-bWxzvPb6N0OubEU4xdTU2j1gX_CvfJxoNwP_DuGsY8PJYihinsVH1SvlVVrnCD-zbu1V8NL9qxTfcBXp_2c_fh8cbf6mlzdfLlcLa8SnZciJqWCtijaussKlaegyJUsL9KiaRdQLTQdikXV6FIjqhLTKkuhUw3oOsurplFlds7eHXX33t2PGKIcTNDY98qiG4NckF4GaZ4RWR9J7V0IHju592ZQ_iAFyGkcciv_GoecxiGhlmQ25b4-VRmb6e4x89F_At6eABW06jvyW5vwh6O30ZqaWB05JE9-GvQyaHJQY2s86ihbZ_6rnY__qOjeWEOFd3jAsHWjt2S6FDKkEuTt9H-m7yMARJEVkP0G3ATFbA</recordid><startdate>20110501</startdate><enddate>20110501</enddate><creator>Torres Macho, Juan, MD</creator><creator>Peña Lillo, Gabriela, MD</creator><creator>Pérez Martínez, David, MD</creator><creator>González Mansilla, Ana, MD</creator><creator>Gámez Díez, Sergio, MD</creator><creator>Mateo Alvarez, Salvador, MD</creator><creator>García de Casasola, Gonzalo, MD</creator><general>Mosby, Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110501</creationdate><title>Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program</title><author>Torres Macho, Juan, MD ; Peña Lillo, Gabriela, MD ; Pérez Martínez, David, MD ; González Mansilla, Ana, MD ; Gámez Díez, Sergio, MD ; Mateo Alvarez, Salvador, MD ; García de Casasola, Gonzalo, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-6a0d55d9f35a420a01634525bd8078c25b587bc6ceea6e27320fab0c9347bba63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Carotid Stenosis - diagnosis</topic><topic>Carotid Stenosis - therapy</topic><topic>Emergency</topic><topic>Emergency and intensive care: techniques, logistics</topic><topic>Emergency Service, Hospital - statistics & numerical data</topic><topic>Female</topic><topic>Humans</topic><topic>Incidence</topic><topic>Intensive care medicine</topic><topic>Intensive care unit. Emergency transport systems. Emergency, hospital ward</topic><topic>Ischemic Attack, Transient - diagnosis</topic><topic>Ischemic Attack, Transient - therapy</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Recurrence</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Stroke - diagnosis</topic><topic>Stroke - therapy</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Torres Macho, Juan, MD</creatorcontrib><creatorcontrib>Peña Lillo, Gabriela, MD</creatorcontrib><creatorcontrib>Pérez Martínez, David, MD</creatorcontrib><creatorcontrib>González Mansilla, Ana, MD</creatorcontrib><creatorcontrib>Gámez Díez, Sergio, MD</creatorcontrib><creatorcontrib>Mateo Alvarez, Salvador, MD</creatorcontrib><creatorcontrib>García de Casasola, Gonzalo, MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of emergency medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Torres Macho, Juan, MD</au><au>Peña Lillo, Gabriela, MD</au><au>Pérez Martínez, David, MD</au><au>González Mansilla, Ana, MD</au><au>Gámez Díez, Sergio, MD</au><au>Mateo Alvarez, Salvador, MD</au><au>García de Casasola, Gonzalo, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program</atitle><jtitle>Annals of emergency medicine</jtitle><addtitle>Ann Emerg Med</addtitle><date>2011-05-01</date><risdate>2011</risdate><volume>57</volume><issue>5</issue><spage>510</spage><epage>516</epage><pages>510-516</pages><issn>0196-0644</issn><eissn>1097-6760</eissn><coden>AEMED3</coden><abstract>Study objective Management of patients with transient ischemic attack varies widely. The aim of this study is to analyze the outcomes of patients with transient ischemic attacks or minor stroke managed in the emergency department (ED) on an outpatient basis and to identify risk factors associated with stroke recurrence. Methods We prospectively analyzed 97 patients with transient ischemic attack or minor stroke who were treated with a standard diagnostic and therapeutic protocol in the ED by emergency physicians. Factors in previous reports were analyzed in relation with a new neurologic event at 90 days or the presence of a severe extracranial carotid stenosis. Results Incidence of recurrent transient ischemic attack or stroke was 7.2% at 24 hours, 9.3 % at 1 week, and 23.7 % at 3 months. Overall incidence of moderate to severe stroke was 0%, 1%, and 5% at the same points, and in outpatients was 0%, 0%, and 4.2%. ABCD2 scoring in these patients predicted stroke rates of 6% at 7 days and 9.9% at 90 days. Conclusion Patients with transient ischemic attack of atherothrombotic origin can be safely treated at the ED with an exhaustive diagnostic and therapeutic protocol. The rates of stroke recurrence obtained in our study are comparable with those in previous studies that show low recurrence risk.</abstract><cop>New York, NY</cop><pub>Mosby, Inc</pub><pmid>21131102</pmid><doi>10.1016/j.annemergmed.2010.09.009</doi><tpages>7</tpages></addata></record> |
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subjects | Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Carotid Stenosis - diagnosis Carotid Stenosis - therapy Emergency Emergency and intensive care: techniques, logistics Emergency Service, Hospital - statistics & numerical data Female Humans Incidence Intensive care medicine Intensive care unit. Emergency transport systems. Emergency, hospital ward Ischemic Attack, Transient - diagnosis Ischemic Attack, Transient - therapy Kaplan-Meier Estimate Male Medical sciences Prognosis Prospective Studies Recurrence Risk Factors Severity of Illness Index Stroke - diagnosis Stroke - therapy Time Factors Treatment Outcome |
title | Outcomes of Atherothrombotic Transient Ischemic Attack and Minor Stroke in an Emergency Department: Results of an Outpatient Management Program |
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