Ion Binding to KcsA: Implications in Ion Selectivity and Channel Gating

Binding of K+ and Na+ to the potassium channel KcsA has been characterized from the stabilization observed in the heat-induced denaturation of the protein as the ion concentration is increased. KcsA thermal denaturation is known to include (i) dissociation of the homotetrameric channel into its cons...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2010-11, Vol.49 (44), p.9480-9487
Hauptverfasser:	Renart, M. L, Triano, I, Poveda, J. A, Encinar, J. A, Fernández, A. M, Ferrer-Montiel, A. V, Gómez, J, González Ros, J. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Binding Sites Models, Molecular Mutation Potassium - metabolism Potassium Channels - chemistry Potassium Channels - genetics Potassium Channels - metabolism Protein Binding Protein Denaturation Protein Structure, Tertiary Sodium - metabolism Streptomyces lividans - chemistry Streptomyces lividans - genetics Streptomyces lividans - metabolism Temperature Tryptophan - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!