First mutation in the βA2-crystallin encoding gene is associated with small lenses and age-related cataracts

A new mouse mutant with small lenses was identified within a mutagenesis screen. The aim of the study was to determine its molecular and morphologic characterization. The offspring of paternally N-ethyl-N-nitrosourea (ENU)-treated C57BL/6J mice were analyzed for eye-size parameters by noninvasive in...

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Veröffentlicht in:Investigative ophthalmology & visual science 2011-04, Vol.52 (5), p.2571-2576
Hauptverfasser: Puk, Oliver, Ahmad, Nafees, Wagner, Sibylle, Hrabé de Angelis, Martin, Graw, Jochen
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Sprache:eng
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