Psychomotor functioning and alertness with guanfacine extended release in subjects with attention-deficit/hyperactivity disorder

To determine whether treatment with guanfacine extended release (GXR) in subjects with attention-deficit/hyperactivity disorder (ADHD) disrupted psychomotor functioning and alertness, or impacted daytime sleepiness. This was a randomized, double-blind, placebo-controlled, multicenter, phase 2, dose-...

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Veröffentlicht in:	Journal of child and adolescent psychopharmacology 2011-04, Vol.21 (2), p.111-120
Hauptverfasser:	Kollins, Scott H, López, Frank A, Vince, Bradley D, Turnbow, John M, Farrand, Kimberly, Lyne, Andrew, Wigal, Sharon B, Roth, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adrenergic alpha-2 Receptor Agonists - administration & dosage Adrenergic alpha-2 Receptor Agonists - adverse effects Adrenergic alpha-2 Receptor Agonists - therapeutic use Alertness (Psychology) Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - psychology Attention deficit hyperactivity disorder Child Children & youth Clinical trials Delayed-Action Preparations Disorders of Excessive Somnolence - chemically induced Disorders of Excessive Somnolence - drug therapy Dosage and administration Dose-Response Relationship, Drug Double-Blind Method Drug Administration Schedule Drug therapy Evaluation Fatigue - chemically induced Fatigue - drug therapy Female Guanfacine Guanfacine - administration & dosage Guanfacine - adverse effects Guanfacine - therapeutic use Humans Male Patient outcomes Placebos Psychiatric Status Rating Scales Psychomotor Performance - drug effects Treatment Outcome
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