Results of medical treatment and metabolic risk factors in children with urolithiasis
Data on conservative treatment in children with urolithiasis are limited. The aim of the study was to determine the metabolic etiology and results of conservative treatment in children with urolithiasis. We evaluated the clinical presentation and metabolic features of 112 children with urolithiasis....
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| Veröffentlicht in: | Pediatric nephrology (Berlin, West) West), 2011-06, Vol.26 (6), p.933-937 |
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| description | Data on conservative treatment in children with urolithiasis are limited. The aim of the study was to determine the metabolic etiology and results of conservative treatment in children with urolithiasis. We evaluated the clinical presentation and metabolic features of 112 children with urolithiasis. The mean age at diagnosis of urolithiasis was 3.9 (range 0.1–18) years, and follow-up duration was 16.7 (range 1–36) months. The most common presenting symptoms were flank or abdominal pain and restlessness (25%). Urine analysis revealed metabolic abnormalities in 92% of cases, including hypocitraturia (42%), hyperoxaluria (32.1%), hypercalcuria (25%), hyperuricosuria (9.8%), and cystinuria (2.7%). Patients who had metabolic risk factors were treated according to underlying metabolic abnormalities. About half of these patients were stone free or stones were diminished in size. These results showed that early recognition and treatment of urinary metabolic abnormalities will reduce the number of invasive procedures and renal damage in children with urolithiasis. |
| doi_str_mv | 10.1007/s00467-011-1803-3 |
| format | Article |
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The aim of the study was to determine the metabolic etiology and results of conservative treatment in children with urolithiasis. We evaluated the clinical presentation and metabolic features of 112 children with urolithiasis. The mean age at diagnosis of urolithiasis was 3.9 (range 0.1–18) years, and follow-up duration was 16.7 (range 1–36) months. The most common presenting symptoms were flank or abdominal pain and restlessness (25%). Urine analysis revealed metabolic abnormalities in 92% of cases, including hypocitraturia (42%), hyperoxaluria (32.1%), hypercalcuria (25%), hyperuricosuria (9.8%), and cystinuria (2.7%). Patients who had metabolic risk factors were treated according to underlying metabolic abnormalities. About half of these patients were stone free or stones were diminished in size. These results showed that early recognition and treatment of urinary metabolic abnormalities will reduce the number of invasive procedures and renal damage in children with urolithiasis.</description><subject>Adolescent</subject><subject>Calcium Metabolism Disorders - complications</subject><subject>Calcium Metabolism Disorders - diet therapy</subject><subject>Calcium Metabolism Disorders - metabolism</subject><subject>Calculi, Urinary</subject><subject>Care and treatment</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children</subject><subject>Citric Acid - urine</subject><subject>Cystinuria - diagnosis</subject><subject>Cystinuria - urine</subject><subject>Development and progression</subject><subject>Diagnosis</subject><subject>Female</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Hypercalciuria - diagnosis</subject><subject>Hypercalciuria - urine</subject><subject>Hyperoxaluria - diagnosis</subject><subject>Hyperoxaluria - urine</subject><subject>Infant</subject><subject>Male</subject><subject>Medical treatment</subject><subject>Medicine & Public Health</subject><subject>Metabolic diseases</subject><subject>Metabolism</subject><subject>Nephrology</subject><subject>Original Article</subject><subject>Patients</subject><subject>Pediatric research</subject><subject>Pediatrics</subject><subject>Phosphates - urine</subject><subject>Potassium</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Sodium</subject><subject>Statistical analysis</subject><subject>Statistics</subject><subject>Toy industry</subject><subject>Treatment Outcome</subject><subject>Uric Acid - urine</subject><subject>Urinalysis</subject><subject>Urinary tract diseases</subject><subject>Urinary tract infections</subject><subject>Urine</subject><subject>Urogenital system</subject><subject>Urolithiasis - complications</subject><subject>Urolithiasis - diet therapy</subject><subject>Urolithiasis - metabolism</subject><subject>Urology</subject><issn>0931-041X</issn><issn>1432-198X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkl9rFTEQxRdR7LX6AXyRBUGftmaS3ST7WIr_oCCIhb6FbDa5m5pNapKl-O3N5VbdyrWUPAQmv3NmwpyqegnoBBBi7xJCLWUNAmiAI9KQR9UGWoIb6Pnl42qDegINauHyqHqW0hVCiHecPq2OMJAWUUCb6uKrTovLqQ6mnvVolXR1jlrmWftcSz-WapZDcFbV0abvtZEqh5hq62s1WTdG7esbm6d6iQXKk5XJpufVEyNd0i9u7-Pq4sP7b2efmvMvHz-fnZ43irYkN9oMvWIwdOU3WHFF-cjJCJhzTA0eQI89Mq3sATOqR6Y6RM3QtYwZTLlRjBxXb_e-1zH8WHTKYrZJaeek12FJglPMetxTKOTrf8irsERfhhOA-q4rHRH6S22l08J6E3KUaucpTiniGChr4V6KEGg5Zy0tVHOA2mqvo3TBa2NL-Y7rQ_i1_8kBvpxRz1YdbPAgwbrDm5Vg0tLlKQW3ZBt8uut8L7h2hD2oYkgpaiOuo51l_FmWIHaRFvtIixJpsYu0IEXz6nZzy1AS-kfxO8MFwHsglSe_1XG92v-5_gKVR_rV</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Gurgoze, Metin Kaya</creator><creator>Sari, Mehmet Yusuf</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20110601</creationdate><title>Results of medical treatment and metabolic risk factors in children with urolithiasis</title><author>Gurgoze, Metin Kaya ; Sari, Mehmet Yusuf</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c643t-efb9c71b51002c8c68d83d128826f2b1ed90f4a91276ed7c506fb5477f268fc73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Calcium Metabolism Disorders - complications</topic><topic>Calcium Metabolism Disorders - diet therapy</topic><topic>Calcium Metabolism Disorders - metabolism</topic><topic>Calculi, Urinary</topic><topic>Care and treatment</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children</topic><topic>Citric Acid - urine</topic><topic>Cystinuria - diagnosis</topic><topic>Cystinuria - urine</topic><topic>Development and progression</topic><topic>Diagnosis</topic><topic>Female</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Hypercalciuria - diagnosis</topic><topic>Hypercalciuria - urine</topic><topic>Hyperoxaluria - diagnosis</topic><topic>Hyperoxaluria - urine</topic><topic>Infant</topic><topic>Male</topic><topic>Medical treatment</topic><topic>Medicine & Public Health</topic><topic>Metabolic diseases</topic><topic>Metabolism</topic><topic>Nephrology</topic><topic>Original Article</topic><topic>Patients</topic><topic>Pediatric research</topic><topic>Pediatrics</topic><topic>Phosphates - urine</topic><topic>Potassium</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Sodium</topic><topic>Statistical analysis</topic><topic>Statistics</topic><topic>Toy industry</topic><topic>Treatment Outcome</topic><topic>Uric Acid - urine</topic><topic>Urinalysis</topic><topic>Urinary tract diseases</topic><topic>Urinary tract infections</topic><topic>Urine</topic><topic>Urogenital system</topic><topic>Urolithiasis - complications</topic><topic>Urolithiasis - diet therapy</topic><topic>Urolithiasis - metabolism</topic><topic>Urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gurgoze, Metin Kaya</creatorcontrib><creatorcontrib>Sari, Mehmet Yusuf</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Pediatric nephrology (Berlin, West)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gurgoze, Metin Kaya</au><au>Sari, Mehmet Yusuf</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Results of medical treatment and metabolic risk factors in children with urolithiasis</atitle><jtitle>Pediatric nephrology (Berlin, West)</jtitle><stitle>Pediatr Nephrol</stitle><addtitle>Pediatr Nephrol</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>26</volume><issue>6</issue><spage>933</spage><epage>937</epage><pages>933-937</pages><issn>0931-041X</issn><eissn>1432-198X</eissn><abstract>Data on conservative treatment in children with urolithiasis are limited. The aim of the study was to determine the metabolic etiology and results of conservative treatment in children with urolithiasis. We evaluated the clinical presentation and metabolic features of 112 children with urolithiasis. The mean age at diagnosis of urolithiasis was 3.9 (range 0.1–18) years, and follow-up duration was 16.7 (range 1–36) months. The most common presenting symptoms were flank or abdominal pain and restlessness (25%). Urine analysis revealed metabolic abnormalities in 92% of cases, including hypocitraturia (42%), hyperoxaluria (32.1%), hypercalcuria (25%), hyperuricosuria (9.8%), and cystinuria (2.7%). Patients who had metabolic risk factors were treated according to underlying metabolic abnormalities. About half of these patients were stone free or stones were diminished in size. These results showed that early recognition and treatment of urinary metabolic abnormalities will reduce the number of invasive procedures and renal damage in children with urolithiasis.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>21340610</pmid><doi>10.1007/s00467-011-1803-3</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Calcium Metabolism Disorders - complications Calcium Metabolism Disorders - diet therapy Calcium Metabolism Disorders - metabolism Calculi, Urinary Care and treatment Child Child, Preschool Children Citric Acid - urine Cystinuria - diagnosis Cystinuria - urine Development and progression Diagnosis Female Health aspects Humans Hypercalciuria - diagnosis Hypercalciuria - urine Hyperoxaluria - diagnosis Hyperoxaluria - urine Infant Male Medical treatment Medicine & Public Health Metabolic diseases Metabolism Nephrology Original Article Patients Pediatric research Pediatrics Phosphates - urine Potassium Prospective Studies Risk Factors Sodium Statistical analysis Statistics Toy industry Treatment Outcome Uric Acid - urine Urinalysis Urinary tract diseases Urinary tract infections Urine Urogenital system Urolithiasis - complications Urolithiasis - diet therapy Urolithiasis - metabolism Urology |
| title | Results of medical treatment and metabolic risk factors in children with urolithiasis |
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