Increased liver-infiltrating CD8+ FoxP3+ regulatory T cells are associated with tumor stage in hepatocellular carcinoma patients

Abstract Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver, and patients who are diagnosed with this tumor typically have a poor prognosis. The suppressive effects of CD4+ FoxP3+ regulatory T cells on antitumor immune response in HCC have been studied in great de...

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Veröffentlicht in:	Human immunology 2010-12, Vol.71 (12), p.1180-1186
Hauptverfasser:	Yang, Zhi-Qing, Yang, Zhan-Yu, Zhang, Lei-Da, Ping-Bie, Wang, Shu-Guang, Ma, Kuan-Sheng, Li, Xiao-Wu, Dong, Jia-Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Allergy and Immunology Carcinoma, Hepatocellular - immunology Carcinoma, Hepatocellular - pathology CD8 + T cells CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism Disease Progression Female Forkhead Transcription Factors - metabolism FoxP3 Hepatocellular carcinoma Humans Liver - immunology Liver - pathology Liver Neoplasms - immunology Liver Neoplasms - pathology Lymphocyte Activation Lymphocytes, Tumor-Infiltrating - immunology Male Middle Aged Neoplasm Staging Regulatory T cells T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism
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