Stimulatory Effect of LPS and Feedback Effect of PGE2 on IL‐27 production

Interleukin (IL)‐27 is a new member of the IL‐6/IL‐12 family, composed of two subunits, the Epstein-Barr virus-induced gene 3 (EBI3) and p28 chains (p28), and produced by activated monocytes and dendritic cells. IL‐27 plays an important role in the regulation of differentiation of naive T helper cel...

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Veröffentlicht in:	Scandinavian journal of immunology 2010-12, Vol.72 (6), p.469-475
Hauptverfasser:	Zhu, C.L, Cao, Y.H, Zhang, R, Song, Y, Liu, W.Y, Pan, F, Li, Y, Zhu, Y, Liu, F, Wu, J.G
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cyclooxygenase 2 - metabolism Cyclooxygenase-2 Dendritic cells Differentiation Dinoprostone - metabolism Dose-Response Relationship, Immunologic Feedback Feedback, Physiological Gene expression Helper cells Humans Inflammatory diseases Interleukin 27 Interleukin 6 Interleukin-17 - immunology Interleukin-17 - metabolism Lipopolysaccharides Lipopolysaccharides - immunology Lymphocytes T Monocytes Monocytes - immunology NF- Kappa B protein Prostaglandin E2
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