Amino Acid Profiles in Human Tear Fluids Analyzed by High-Performance Liquid Chromatography and Electrospray Ionization Tandem Mass Spectrometry

Purpose To identify the 23 amino acid profiles in human tear fluids, and to evaluate whether the ocular disease conditions reflect the amino acid profiles. Design Laboratory investigation. Methods We evaluated the concentrations and relative composition of 23 amino acids in tear fluids obtained from...

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Veröffentlicht in:	American journal of ophthalmology 2011-05, Vol.151 (5), p.799-808.e1
Hauptverfasser:	Nakatsukasa, Mina, Sotozono, Chie, Shimbo, Kazutaka, Ono, Nobukazu, Miyano, Hiroshi, Okano, Akira, Hamuro, Junji, Kinoshita, Shigeru
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging - physiology Amino acids Amino Acids - metabolism Aqueous Humor - metabolism Biological and medical sciences Chromatography, High Pressure Liquid Cluster analysis Colleges & universities Conjunctival Diseases - metabolism Corneal Diseases - metabolism Disease Female Gene expression Homeostasis Humans Male Medical sciences Metabolites Miscellaneous Ophthalmology Protein synthesis Proteins Science Scleral Diseases - metabolism Spectrometry, Mass, Electrospray Ionization Stevens-Johnson Syndrome - metabolism Tandem Mass Spectrometry Tears - metabolism Young Adult
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