Impact of early developmental arsenic exposure on promotor CpG-island methylation of genes involved in neuronal plasticity

► Chronic arsenic exposure alters the DNA methylation pattern in cortex and hippocampus of rats. ► The promotor regions of reelin and protein phosphatase 1 genes undergo methylation changes associated with arsenic exposure. ► Chronic low-level arsenic exposure is associated with progressive and dose...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurochemistry international 2011-04, Vol.58 (5), p.574-581
Hauptverfasser:	Martínez, Liborio, Jiménez, Verónica, García-Sepúlveda, Christian, Ceballos, Fátima, Delgado, Juan Manuel, Niño-Moreno, Perla, Doniz, Lesly, Saavedra-Alanís, Víctor, Castillo, Claudia G., Santoyo, Martha E., González-Amaro, Roberto, Jiménez-Capdeville, María E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age Factors Animal models Animals Arsenic Arsenic - administration & dosage Arsenic - toxicity Biological and medical sciences Brain Brain - drug effects Brain - growth & development Children Cognitive ability Cortex (frontal) CpG Islands - drug effects CpG Islands - physiology DNA methylation DNA Methylation - drug effects DNA Methylation - physiology Drinking water Epigenetic regulation epigenetics Fear Female Flow cytometry Fundamental and applied biological sciences. Psychology Gestation Hippocampus Immunohistochemistry Learning Male Memory Neuromodulation Neuronal plasticity Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Neurotoxicity Phosphoprotein phosphatase Plasticity (neural) Polymerase chain reaction Promoter Regions, Genetic - drug effects Promoter Regions, Genetic - physiology Promoters Rats Rats, Wistar Reelin protein Toxicity Vertebrates: nervous system and sense organs Wistar rat
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!