Energy metabolism in adult neural stem cell fate

The adult mammalian brain contains a population of neural stem cells that can give rise to neurons, astrocytes, and oligodendrocytes and are thought to be involved in certain forms of memory, behavior, and brain injury repair. Neural stem cell properties, such as self-renewal and multipotency, are m...

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Veröffentlicht in:	Progress in neurobiology 2011-02, Vol.93 (2), p.182-203
Hauptverfasser:	Rafalski, Victoria A, Brunet, Anne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate Kinase - metabolism Aging - physiology Animals Cell Differentiation - physiology Energy Metabolism Humans Hypoxia-Inducible Factor 1 - metabolism Neural Stem Cells - cytology Neural Stem Cells - physiology Neurons - cytology Neurons - physiology Oxidation-Reduction Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism PTEN Phosphohydrolase - metabolism Signal Transduction - physiology Sirtuins - metabolism TOR Serine-Threonine Kinases - metabolism
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