Skin regeneration with bone marrow-derived cell populations
Bone marrow-derived cells of distinct differentiation level could differently influence the process of skin regeneration. The results of our study revealed that hematopoietic stem cells (HSC) population influenced the repair of injured tissue slower in comparison with lineage negative (lin −) cell p...
Gespeichert in:
| Veröffentlicht in: | International immunopharmacology 2010-12, Vol.10 (12), p.1548-1551 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1551 |
|---|---|
| container_issue | 12 |
| container_start_page | 1548 |
| container_title | International immunopharmacology |
| container_volume | 10 |
| creator | RAMANAUSKAITE, Giedre KASETA, Vytautas VAITKUVIENE, Aida BIZIULEVICIENE, Gene |
| description | Bone marrow-derived cells of distinct differentiation level could differently influence the process of skin regeneration. The results of our study revealed that hematopoietic stem cells (HSC) population influenced the repair of injured tissue slower in comparison with lineage negative (lin
−) cell population containing not only HSC but also cell progenitors of different differentiation levels. Wound healing process was faster in lin
− cell suspension treated group, the stage of proliferation was more intensive and increased number of skin appendages occurred. The adaptation of purified HSC at the site of injury was longer and the stages of wound healing took place later. The results obtained show that in further experiments the complex procedure of HSC isolation and purification could be shortened and heavy skin injuries could be successfully treated with the help of lin
− cell population.
► Lin– cell population inhibits the inflammation stage of wound healing. ► Lin– cell population stimulate the proliferation stage of wound healing. ► Lin– cell population influence injured skin re-epithelisation. |
| doi_str_mv | 10.1016/j.intimp.2010.09.003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_862781362</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1567576910002845</els_id><sourcerecordid>862781362</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-9c444c1dc40a4c1efc44c16a09e0832ea97d91bb196753f9dedd12047e2811f33</originalsourceid><addsrcrecordid>eNqFkE1P3DAQQK2qVVm2_QcI5VJxynYcf8VCQkIroEhIHKBny2tPqLfZJNgJqP8eb3cLN3rxeEZv7JlHyBGFBQUqv68XoRvDZlhUkEugFwDsA5nRWtUlVSA-5ruQqhRK6gNymNIaINc5_UwOKqhlrYSYkdO736ErIj5gh9GOoe-K5zD-KlZ9h8XGxtg_lx5jeEJfOGzbYuiHqf0Lpi_kU2PbhF_3cU5-Xl7cL3-UN7dX18vzm9Lxio2ldpxzR73jYHPExm1TaUEj1KxCq5XXdLWiWirBGu3Re1oBV1jVlDaMzcnJ7t0h9o8TptFsQtoOYzvsp2RqWamaMln9n6RCcJHPTPId6WKfUsTGDDHkff8YCmbr16zNzq_Z-jWgTfab2473H0yrDfrXpn9CM_BtD9jkbNtE27mQ3jgmGYCGzJ3tOMzingJGk1zAzqEPEd1ofB_en-QFXXKaIQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>815545815</pqid></control><display><type>article</type><title>Skin regeneration with bone marrow-derived cell populations</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>RAMANAUSKAITE, Giedre ; KASETA, Vytautas ; VAITKUVIENE, Aida ; BIZIULEVICIENE, Gene</creator><creatorcontrib>RAMANAUSKAITE, Giedre ; KASETA, Vytautas ; VAITKUVIENE, Aida ; BIZIULEVICIENE, Gene</creatorcontrib><description>Bone marrow-derived cells of distinct differentiation level could differently influence the process of skin regeneration. The results of our study revealed that hematopoietic stem cells (HSC) population influenced the repair of injured tissue slower in comparison with lineage negative (lin
−) cell population containing not only HSC but also cell progenitors of different differentiation levels. Wound healing process was faster in lin
− cell suspension treated group, the stage of proliferation was more intensive and increased number of skin appendages occurred. The adaptation of purified HSC at the site of injury was longer and the stages of wound healing took place later. The results obtained show that in further experiments the complex procedure of HSC isolation and purification could be shortened and heavy skin injuries could be successfully treated with the help of lin
− cell population.
► Lin– cell population inhibits the inflammation stage of wound healing. ► Lin– cell population stimulate the proliferation stage of wound healing. ► Lin– cell population influence injured skin re-epithelisation.</description><identifier>ISSN: 1567-5769</identifier><identifier>EISSN: 1878-1705</identifier><identifier>DOI: 10.1016/j.intimp.2010.09.003</identifier><identifier>PMID: 20868755</identifier><language>eng</language><publisher>Kidlington: Elsevier B.V</publisher><subject>Animals ; Antigens, Ly - immunology ; Biological and medical sciences ; Bone Marrow Cells - cytology ; Bone Marrow Cells - immunology ; Cell Differentiation - immunology ; Cell Lineage - immunology ; Female ; Full-thickness skin wound ; Hematopoietic Stem Cell Transplantation ; Hematopoietic Stem Cells - cytology ; Hematopoietic Stem Cells - immunology ; Medical sciences ; Membrane Proteins - immunology ; Mice ; Mice, Inbred BALB C ; Murine bone marrow-derived cells ; Pharmacology. Drug treatments ; Proto-Oncogene Proteins c-kit - immunology ; Regeneration - immunology ; Skin - cytology ; Skin - immunology ; Skin - injuries ; Skin Physiological Phenomena - immunology ; Skin regeneration ; Wound Healing - immunology</subject><ispartof>International immunopharmacology, 2010-12, Vol.10 (12), p.1548-1551</ispartof><rights>2010 Elsevier B.V.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-9c444c1dc40a4c1efc44c16a09e0832ea97d91bb196753f9dedd12047e2811f33</citedby><cites>FETCH-LOGICAL-c423t-9c444c1dc40a4c1efc44c16a09e0832ea97d91bb196753f9dedd12047e2811f33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.intimp.2010.09.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23630090$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20868755$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RAMANAUSKAITE, Giedre</creatorcontrib><creatorcontrib>KASETA, Vytautas</creatorcontrib><creatorcontrib>VAITKUVIENE, Aida</creatorcontrib><creatorcontrib>BIZIULEVICIENE, Gene</creatorcontrib><title>Skin regeneration with bone marrow-derived cell populations</title><title>International immunopharmacology</title><addtitle>Int Immunopharmacol</addtitle><description>Bone marrow-derived cells of distinct differentiation level could differently influence the process of skin regeneration. The results of our study revealed that hematopoietic stem cells (HSC) population influenced the repair of injured tissue slower in comparison with lineage negative (lin
−) cell population containing not only HSC but also cell progenitors of different differentiation levels. Wound healing process was faster in lin
− cell suspension treated group, the stage of proliferation was more intensive and increased number of skin appendages occurred. The adaptation of purified HSC at the site of injury was longer and the stages of wound healing took place later. The results obtained show that in further experiments the complex procedure of HSC isolation and purification could be shortened and heavy skin injuries could be successfully treated with the help of lin
− cell population.
► Lin– cell population inhibits the inflammation stage of wound healing. ► Lin– cell population stimulate the proliferation stage of wound healing. ► Lin– cell population influence injured skin re-epithelisation.</description><subject>Animals</subject><subject>Antigens, Ly - immunology</subject><subject>Biological and medical sciences</subject><subject>Bone Marrow Cells - cytology</subject><subject>Bone Marrow Cells - immunology</subject><subject>Cell Differentiation - immunology</subject><subject>Cell Lineage - immunology</subject><subject>Female</subject><subject>Full-thickness skin wound</subject><subject>Hematopoietic Stem Cell Transplantation</subject><subject>Hematopoietic Stem Cells - cytology</subject><subject>Hematopoietic Stem Cells - immunology</subject><subject>Medical sciences</subject><subject>Membrane Proteins - immunology</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Murine bone marrow-derived cells</subject><subject>Pharmacology. Drug treatments</subject><subject>Proto-Oncogene Proteins c-kit - immunology</subject><subject>Regeneration - immunology</subject><subject>Skin - cytology</subject><subject>Skin - immunology</subject><subject>Skin - injuries</subject><subject>Skin Physiological Phenomena - immunology</subject><subject>Skin regeneration</subject><subject>Wound Healing - immunology</subject><issn>1567-5769</issn><issn>1878-1705</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAQQK2qVVm2_QcI5VJxynYcf8VCQkIroEhIHKBny2tPqLfZJNgJqP8eb3cLN3rxeEZv7JlHyBGFBQUqv68XoRvDZlhUkEugFwDsA5nRWtUlVSA-5ruQqhRK6gNymNIaINc5_UwOKqhlrYSYkdO736ErIj5gh9GOoe-K5zD-KlZ9h8XGxtg_lx5jeEJfOGzbYuiHqf0Lpi_kU2PbhF_3cU5-Xl7cL3-UN7dX18vzm9Lxio2ldpxzR73jYHPExm1TaUEj1KxCq5XXdLWiWirBGu3Re1oBV1jVlDaMzcnJ7t0h9o8TptFsQtoOYzvsp2RqWamaMln9n6RCcJHPTPId6WKfUsTGDDHkff8YCmbr16zNzq_Z-jWgTfab2473H0yrDfrXpn9CM_BtD9jkbNtE27mQ3jgmGYCGzJ3tOMzingJGk1zAzqEPEd1ofB_en-QFXXKaIQ</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>RAMANAUSKAITE, Giedre</creator><creator>KASETA, Vytautas</creator><creator>VAITKUVIENE, Aida</creator><creator>BIZIULEVICIENE, Gene</creator><general>Elsevier B.V</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20101201</creationdate><title>Skin regeneration with bone marrow-derived cell populations</title><author>RAMANAUSKAITE, Giedre ; KASETA, Vytautas ; VAITKUVIENE, Aida ; BIZIULEVICIENE, Gene</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-9c444c1dc40a4c1efc44c16a09e0832ea97d91bb196753f9dedd12047e2811f33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Animals</topic><topic>Antigens, Ly - immunology</topic><topic>Biological and medical sciences</topic><topic>Bone Marrow Cells - cytology</topic><topic>Bone Marrow Cells - immunology</topic><topic>Cell Differentiation - immunology</topic><topic>Cell Lineage - immunology</topic><topic>Female</topic><topic>Full-thickness skin wound</topic><topic>Hematopoietic Stem Cell Transplantation</topic><topic>Hematopoietic Stem Cells - cytology</topic><topic>Hematopoietic Stem Cells - immunology</topic><topic>Medical sciences</topic><topic>Membrane Proteins - immunology</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Murine bone marrow-derived cells</topic><topic>Pharmacology. Drug treatments</topic><topic>Proto-Oncogene Proteins c-kit - immunology</topic><topic>Regeneration - immunology</topic><topic>Skin - cytology</topic><topic>Skin - immunology</topic><topic>Skin - injuries</topic><topic>Skin Physiological Phenomena - immunology</topic><topic>Skin regeneration</topic><topic>Wound Healing - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RAMANAUSKAITE, Giedre</creatorcontrib><creatorcontrib>KASETA, Vytautas</creatorcontrib><creatorcontrib>VAITKUVIENE, Aida</creatorcontrib><creatorcontrib>BIZIULEVICIENE, Gene</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>International immunopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RAMANAUSKAITE, Giedre</au><au>KASETA, Vytautas</au><au>VAITKUVIENE, Aida</au><au>BIZIULEVICIENE, Gene</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Skin regeneration with bone marrow-derived cell populations</atitle><jtitle>International immunopharmacology</jtitle><addtitle>Int Immunopharmacol</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>10</volume><issue>12</issue><spage>1548</spage><epage>1551</epage><pages>1548-1551</pages><issn>1567-5769</issn><eissn>1878-1705</eissn><abstract>Bone marrow-derived cells of distinct differentiation level could differently influence the process of skin regeneration. The results of our study revealed that hematopoietic stem cells (HSC) population influenced the repair of injured tissue slower in comparison with lineage negative (lin
−) cell population containing not only HSC but also cell progenitors of different differentiation levels. Wound healing process was faster in lin
− cell suspension treated group, the stage of proliferation was more intensive and increased number of skin appendages occurred. The adaptation of purified HSC at the site of injury was longer and the stages of wound healing took place later. The results obtained show that in further experiments the complex procedure of HSC isolation and purification could be shortened and heavy skin injuries could be successfully treated with the help of lin
− cell population.
► Lin– cell population inhibits the inflammation stage of wound healing. ► Lin– cell population stimulate the proliferation stage of wound healing. ► Lin– cell population influence injured skin re-epithelisation.</abstract><cop>Kidlington</cop><pub>Elsevier B.V</pub><pmid>20868755</pmid><doi>10.1016/j.intimp.2010.09.003</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1567-5769 |
| ispartof | International immunopharmacology, 2010-12, Vol.10 (12), p.1548-1551 |
| issn | 1567-5769 1878-1705 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_862781362 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Animals Antigens, Ly - immunology Biological and medical sciences Bone Marrow Cells - cytology Bone Marrow Cells - immunology Cell Differentiation - immunology Cell Lineage - immunology Female Full-thickness skin wound Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - immunology Medical sciences Membrane Proteins - immunology Mice Mice, Inbred BALB C Murine bone marrow-derived cells Pharmacology. Drug treatments Proto-Oncogene Proteins c-kit - immunology Regeneration - immunology Skin - cytology Skin - immunology Skin - injuries Skin Physiological Phenomena - immunology Skin regeneration Wound Healing - immunology |
| title | Skin regeneration with bone marrow-derived cell populations |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T04%3A32%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Skin%20regeneration%20with%20bone%20marrow-derived%20cell%20populations&rft.jtitle=International%20immunopharmacology&rft.au=RAMANAUSKAITE,%20Giedre&rft.date=2010-12-01&rft.volume=10&rft.issue=12&rft.spage=1548&rft.epage=1551&rft.pages=1548-1551&rft.issn=1567-5769&rft.eissn=1878-1705&rft_id=info:doi/10.1016/j.intimp.2010.09.003&rft_dat=%3Cproquest_cross%3E862781362%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=815545815&rft_id=info:pmid/20868755&rft_els_id=S1567576910002845&rfr_iscdi=true |