Platelet production and destruction in liver cirrhosis

Background & Aims Thrombocytopenia is common in liver cirrhosis (LC) but the mechanisms are not fully understood. The purpose of our work was to evaluate platelet kinetics in LC with different etiologies by examining platelet production and destruction. Methods Ninety-one consecutive LC patients...

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Veröffentlicht in:	Journal of hepatology 2011-05, Vol.54 (5), p.894-900
Hauptverfasser:	Pradella, Paola, Bonetto, Stefania, Turchetto, Stefano, Uxa, Laura, Comar, Consuelo, Zorat, Francesca, De Angelis, Vincenzo, Pozzato, Gabriele
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Anemia, Aplastic - blood Anemia, Aplastic - immunology Anemia, Aplastic - pathology Aplastic anemia Autoantibodies - blood B-Lymphocytes - immunology Biological and medical sciences Blood Platelets - immunology Blood Platelets - metabolism Blood Platelets - pathology Child Female Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen Glycocalicin HBV HCV Hematologic and hematopoietic diseases Humans Idiopathic thrombocytopenic purpura Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Liver cirrhosis Liver Cirrhosis - blood Liver Cirrhosis - immunology Liver Cirrhosis - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Other diseases. Semiology Platelet diseases and coagulopathies Platelet Glycoprotein GPIb-IX Complex - metabolism Purpura, Thrombocytopenic, Idiopathic - blood Purpura, Thrombocytopenic, Idiopathic - immunology Purpura, Thrombocytopenic, Idiopathic - pathology Spleen - pathology Thrombopoiesis - physiology Thrombopoietin Thrombopoietin - blood
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